Anti-Interferon gamma monoclonal antibody NI-0501: A new option to render allogeneic HSCT for HLH safer and more effective?

被引：0

作者：

Locatelli, F. ^{[1
]}

Jordan, M. ^{[2
]}

Allen, C. ^{[3
]}

Cesaro, S. ^{[4
]}

Fagioli, F. ^{[5
]}

Henry, M. ^{[6
]}

Rizzari, C. ^{[7
]}

Rossig, C. ^{[8
]}

Sevilla, J. ^{[9
]}

Ballabio, M. ^{[10
]}

Ferlin, W. ^{[10
]}

De Min, C. ^{[10
]}

机构：

[1] Osped Pediat Bambino Gesu, Dept Pediat Hematol & Oncol, Rome, Italy

[2] Cincinnati Childrens Hosp, Cincinnati, OH USA

[3] Texas Childrens Hosp, Houston, TX 77030 USA

[4] Policlin GB Rossi, Verona, Italy

[5] AO Regina Margherita, Turin, Italy

[6] Phoenix Children Hosp, Phoenix, AZ USA

[7] Osped San Gerardo, Monza, Italy

[8] Univ Childrens Hosp, Munster, Germany

[9] Hosp Univ Nino Jesus, Madrid, Spain

[10] Novimmune Sa, Plan Les Ouates, Switzerland

来源：

BONE MARROW TRANSPLANTATION | 2016年 / 51卷

关键词：

D O I：

暂无

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

O147

引用

页码：S86 / S86

页数：1

共 8 条

[1] A NOVEL TARGETED APPROACH TO THE TREATMENT OF HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH) WITH NI-0501, AN ANTI-INTERFERON GAMMA MONOCLONAL ANTIBODY
Jordan, Michael B.
Locatelli, Franco
Allen, Carl
De Benedetti, Fabrizio
Grom, Alexei
Ballabio, Maria
Ferlin, Walter
De Min, Cristina
JOURNAL OF CLINICAL IMMUNOLOGY, 2016, 36 (03) : 282 - 282
[2] Innovative Approach for the Identification of an Appropriate Dose Regimen of a Targeted Treatment, NI-0501, an Anti-Interferon Gamma (IFNg) Antibody, in Patients with Hemophagocytic Lymphohistiocytosis (HLH)
De Min, Cristina
Jacqmin, Philippe
Laveille, Christian
Nelson, Robert
Guilhot, Florence
Deehan, Maureen
Kosco-Vilbois, Marie
Ferlin, Walter
Lapeyre, Genevieve
ARTHRITIS & RHEUMATOLOGY, 2015, 67
[3] A Novel Targeted Approach to the Treatment of Hemophagocytic Lymphohistiocytosis (HLH) with an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody (mAb), NI-0501: First Results from a Pilot Phase 2 Study in Children with Primary HLH
Jordan, Michael
Locatelli, Franco
Allen, Carl
De Benedetti, Fabrizio
Grom, Alexei A.
Ballabio, Maria
Ferlin, Walter Giovanni
De Min, Cristina
BLOOD, 2015, 126 (23)
[4] Investigating the novel mechanism of action for NI-0501, a human interferon gamma monoclonal antibody
Hatterer, E.
Richard, F.
Malinge, P.
Serge, A.
Startchick, S.
Kosco-Vilbois, M.
Deehan, M.
Ferlin, W.
Guilhot, F.
CYTOKINE, 2012, 59 (03) : 570 - 570
[5] RESPONSE TO NI-0501, AN ANTI- IFNγ MONOCLONAL ANTIBODY, IN A PATIENT WITH REFRACTORY HLH AND MULTIPLE INFECTIOUS COMPLICATIONS
Jordan, Michael
Filipovich, Lisa
Ferlin, Walter
de Min, Cristina
PEDIATRIC BLOOD & CANCER, 2015, 62 : S128 - S129
[6] Emapalumab, an Anti-Interferon Gamma Monoclonal Antibody in Two Patients with NLRC4-Related Disease and Severe Hemophagocytic Lymphohistiocytosis (HLH)
Bracaglia, Claudia
Prencipe, Giusi
Insalaco, Antonella
Caiello, Ivan
Marucci, Giulia
Pecoraro, Raffaele
Pardeo, Manuela
Dolezalova, Pavla
Fingerhutova, Sarka
Ballabio, Maria
de Min, Cristina
De Benedetti, Fabrizio
ARTHRITIS & RHEUMATOLOGY, 2018, 70
[7] POPULATION PHARMACOKINETIC (PK) ANALYSIS OF EMAPALUMAB, A FULLY HUMAN, ANTI-INTERFERON GAMMA (IFNγ) MONOCLONAL ANTIBODY, IN PATIENTS WITH PRIMARY HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH)
Laveille, Christian
Jacqmin, Philippe
de Graaf, Kathy
de Min, Cristina
PEDIATRIC BLOOD & CANCER, 2021, 68
[8] OVERALL RESPONSE RATE (ORR) WITH EMAPALUMAB, A FULLY HUMAN, ANTI-INTERFERON GAMMA MONOCLONAL ANTIBODY, IN PATIENTS WITH PRIMARY HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH): RESULTS OF A SENSITIVITY ANALYSIS
Locatelli, Franco
Jordan, Michael
Allen, Carl
Cesaro, Simone
Rizzari, Carmelo
Rao, Anupama
Degar, Barbara
Garrington, Timothy
Sevilla, Julian
Putti, Maria Caterina
Fagioli, Franca
Ahlmann, Martina
Dapena Diaz, Jose-Luis
Henry, Michael
De Benedetti, Fabrizio
Grom, Alexei
Jacqmin, Philippe
Ballabio, Maria
Stoltenberg, Anna
Vagero, Marten
de Min, Cristina
PEDIATRIC BLOOD & CANCER, 2021, 68

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