Chances and limitations of chemotherapy in elderly patients

被引：0

作者：

Wedding, U. ^{[1
]}

机构：

[1] Univ Klinikum Jena, Klin Innere Med 2, Abt Palliat Med, D-07747 Jena, Germany

来源：

INTERNIST | 2010年 / 51卷 / 03期

关键词：

Chemotherapy; Elderly; Co-morbidity; Functional status; Geriatric assessment; COMPREHENSIVE GERIATRIC ASSESSMENT; ADJUVANT CHEMOTHERAPY; BREAST-CANCER; OLDER WOMEN; POOLED ANALYSIS; COLON-CANCER; PHASE-III; AGE; SURVIVAL; PARTICIPATION;

D O I：

10.1007/s00108-010-2601-x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The chronological age of a patient should not be a barrier to apply chemotherapy. Elderly patients can benefit from chemotherapy. Chronological age should not be a reason for diagnostic or therapeutic nihilism, as the age of a patient poorly characterizes their health situation. Data with high level of evidence on treatment of elderly patients with cancer are limited. A comprehensive geriatric assessment (CGA) describes the individual deficits and resources of a patient much better. Limitations in CGA are risk factors for increased toxicity and decreased treatment benefit. The currently available data demonstrate under- and over-treatment in elderly patients with cancer.

引用

页码：402 / +

页数：6

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