Postoperative radiotherapy in non-small-cell lung cancer: update of an individual patient data meta-analysis

被引：120
|
作者：
Burdett, S [1 ]
Stewart, L [1 ]
机构：
[1] Meta Anal Grp, MRC Clin Trials Unit, London NW1 2DA, England
来源：
LUNG CANCER | 2005年 / 47卷 / 01期
关键词：
meta-analysis; non-small cell lung cancer; radiotherapy; surgery;
D O I：
10.1016/j.lungcan.2004.09.010
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We report an updated systematic review and individual patient data meta-analysis of the effectiveness of postoperative radiotherapy (PORT) in nonsmall-cell lung cancer. Results continue to show PORT to be detrimental, with an 18% relative increase in the risk of death. Similar detriments Were observed for local recurrence-free survival, distant recurrence-free survival and overall recurrence-free survival. There continues to be evidence that the effects of PORT are more harmful in those patients with stage I disease than those with stage 11 disease. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：81 / 83
页数：3
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