Spatiotemporal analysis of optical imaging data

被引:24
|
作者
Sornborger, A
Sailstad, C
Kaplan, E
Sirovich, L
机构
[1] Mt Sinai Sch Med, Biomath Sci Div, Lab Appl Math, New York, NY 10029 USA
[2] Mt Sinai Sch Med, Dept Neurobiol, New York, NY 10029 USA
[3] Mt Sinai Sch Med, Dept Ophthalmol, New York, NY 10029 USA
[4] Mt Sinai Sch Med, Dept Biophys, New York, NY 10029 USA
关键词
D O I
10.1016/S1053-8119(02)00045-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Previous methods for analyzing optical imaging data have relied heavily on temporal averaging. However, response dynamics are rich sources of information. Here, we develop and present a method that combines principal component analysis and multitaper harmonic analysis to extract the statistically significant spatial and temporal response from optical imaging data. We apply the method to both simulated data and experimental optical imaging data from the cat primary visual cortex. (C) 2003 Elsevier Science (USA). All rights reserved.
引用
收藏
页码:610 / 621
页数:12
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