Inhibition of amyloid formation: a strategy to delay the onset of Alzheimer's disease

被引：63
|
作者：
Lansbury, PT
机构：
[1] Brigham & Womens Hosp, Ctr Neurol Dis, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Neurol, Boston, MA 02115 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 1997年 / 1卷 / 02期
关键词：
D O I：
10.1016/S1367-5931(97)80018-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Converging evidence suggests that the formation of amyloid plaques may play a central role in the pathogenesis of Alzheimer's disease and that blocking amyloid formation may be an effective therapeutic strategy. (C) Current Biology Ltd ISSN 1367-5931.
引用
收藏
页码：260 / 267
页数：8
相关论文
共 50 条
  • [1] Bilingualism as a strategy to delay the onset of Alzheimer's disease
    Klimova, Blanka
    Valis, Martin
    Kuca, Kamil
    CLINICAL INTERVENTIONS IN AGING, 2017, 12 : 1731 - 1737
  • [2] Inhibition of amyloid beta-protein formation for the treatment of Alzheimer's disease
    McDonald, IA
    Munoz, B
    Wang, BW
    Li, HZ
    Albrecht, E
    Provow, S
    Farrow, J
    Holtz, G
    Turner, M
    Wagner, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 212 : 212 - MEDI
  • [3] Review on Alzheimer's disease: Inhibition of amyloid beta and tau tangle formation
    Ashrafian, Hossein
    Zadeh, Elaheh Hadi
    Khan, Rizwan Hasan
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 167 : 382 - 394
  • [4] Inhibition of Amyloid-β Aggregation in Alzheimer's Disease
    Wang, Qiuming
    Yu, Xiang
    Li, Lingyan
    Zheng, Jie
    CURRENT PHARMACEUTICAL DESIGN, 2014, 20 (08) : 1223 - 1243
  • [5] Brain Amyloid in Sporadic Young Onset Alzheimer's Disease
    Panegyres, Peter K.
    Robins, Peter
    JOURNAL OF ALZHEIMERS DISEASE REPORTS, 2023, 7 (01) : 263 - 270
  • [6] Amyloid Deposition in Early Onset versus Late Onset Alzheimer's Disease
    Cho, Hanna
    Seo, Sang Won
    Kim, Jung-Hyun
    Suh, Mee Kyung
    Lee, Jae-Hong
    Choe, Yearn Seong
    Lee, Kyung-Han
    Kim, Jae Seung
    Kim, Geon Ha
    Noh, Young
    Ye, Byoung Seok
    Kim, Hee Jin
    Yoon, Cindy W.
    Chin, Juhee
    Na, Duk L.
    JOURNAL OF ALZHEIMERS DISEASE, 2013, 35 (04) : 813 - 821
  • [7] Mechanism of Alzheimer's disease?Amyloid Formation and Regulation
    Xu, H. X.
    JOURNAL OF ALZHEIMERS DISEASE, 2002, 4 (01) : 49 - 49
  • [8] Can Nutrients Prevent or Delay Onset of Alzheimer's Disease?
    Kamphuis, Patrick J. G. H.
    Scheltens, Philip
    JOURNAL OF ALZHEIMERS DISEASE, 2010, 20 (03) : 765 - 775
  • [9] Can immunization with BCG delay the onset of Alzheimer's disease?
    Gofrit, Ofer N.
    Greenblatt, Charles L.
    Klein, Benjamin Y.
    Ben-Hur, Tamir
    Bercovier, Herve
    GERIATRICS & GERONTOLOGY INTERNATIONAL, 2023, 23 (11) : 889 - 890
  • [10] Survival and pharmacotherapy delay in young onset Alzheimer's disease
    Stojkovic, Tanja
    Stojmenovic, Gorana Mandic
    Sarcevic, Maksim
    Stefanova, Elka
    Obradovic, Dragan
    Kostic, Vladimir S.
    ALZHEIMERS & DEMENTIA, 2023, 19
12345