Risk factors for hepatitis E virus infection and disease

被引：35
|
作者：
Kmush, Brittany L. [1 ]
Nelson, Kenrad E. [2 ]
Labrique, Alain B. [1 ,2 ]
机构：
[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD 21205 USA
[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA
来源：
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY | 2015年 / 13卷 / 01期
关键词：
asymptomatic infection; epidemiology; hepatitis E; hepatitis E virus; risk factors; severe disease; ORGAN-TRANSPLANT RECIPIENTS; RURAL EGYPTIAN COMMUNITIES; CHRONIC LIVER-DISEASE; SOUTHWEST ENGLAND; SOUTHERN INDIA; HEV INFECTION; IMMUNOGLOBULIN-M; E SEROPREVALENCE; LARGE OUTBREAK; BLOOD-DONORS;
D O I：
10.1586/14787210.2015.981158
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Hepatitis E, caused by hepatitis E virus, is a disease of global significance, causing 20 million infections each year. Genotypes 1 and 2 have vastly different epidemiological patterns from genotypes 3 and 4. In genotype 1 and 2 endemic areas, most infections and illness occur in persons 15-30 years of age, with pregnant women being the most likely to experience severe disease. In genotype 3 and 4 endemic areas, most infections and illness occur in those of age 40-60 years, with males representing a large portion of those with severe disease. However, the lack of an easily accessible serologic assay in many countries continues to be a barrier to the diagnosis and recognition of hepatitis E virus.
引用
收藏
页码：41 / 53
页数：13
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