Diffuse bone metastases on 68Ga-PSMA PET-CT in a patient with prostate cancer and normal bone scan

被引：8
|
作者：
Lavalaye, J. [1 ]
Kaldeway, P. [1 ]
van Melick, H. H. E. [2 ]
机构：
[1] Sint Antonius Ziekenhuis, Dept Nucl Med, Nieuwegein, Netherlands
[2] Sint Antonius Ziekenhuis, Dept Urol, Nieuwegein, Netherlands
来源：
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING | 2016年 / 43卷 / 08期
关键词：
68Ga-PSMA; PET-CT; Prostate cancer;
D O I：
10.1007/s00259-016-3398-1
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 75-year-old patient was diagnosed with a Gleason 9 prostate carcinoma. His PSA level was 50.4 ng/ml. Routine bone scintigraphy was negative for metastasis (a). Due to the high tumour grading and relatively high PSA level, Ga-68-PSMA PET-CT was ordered to rule out distant metastases. This scan showed numerous skeletal lesions with high tracer accumulation as sign of diffuse osseous metastases (b). On low-dose CT there were no signs of sclerosis (c). Ga-68-PSMA PET-CT also showed high uptake in the prostate and in para-iliac and para-aortal lymph nodes, without lymph node enlargement. No bone biopsy was obtained to confirm the metastases. Due to this result, the treatment plan was changed to systemic therapy, instead of local therapy.
引用
收藏
页码：1563 / 1564
页数：2
相关论文
共 50 条
  • [1] Diffuse bone metastases on 68Ga-PSMA PET-CT in a patient with prostate cancer and normal bone scan
    J. Lavalaye
    P. Kaldeway
    H. H. E. van Melick
    [J]. European Journal of Nuclear Medicine and Molecular Imaging, 2016, 43 : 1563 - 1564
  • [2] 68Ga-PSMA PET/CT in the evaluation of bone metastases in prostate cancer
    Sachpekidis, Christos
    Baeumer, P.
    Kopka, K.
    Hadaschik, B. A.
    Hohenfellner, M.
    Kopp-Schneider, A.
    Haberkorn, U.
    Dimitrakopoulou-Strauss, A.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2018, 45 (06) : 904 - 912
  • [3] 68Ga-PSMA PET/CT in the evaluation of bone metastases in prostate cancer
    Christos Sachpekidis
    P. Bäumer
    K. Kopka
    B. A. Hadaschik
    M. Hohenfellner
    A. Kopp-Schneider
    U. Haberkorn
    A. Dimitrakopoulou-Strauss
    [J]. European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45 : 904 - 912
  • [4] Comparison of hybrid 68Ga-PSMA PET/MRI and 68Ga-PSMA PET/CT in the evaluation of lymph node and bone metastases of prostate cancer
    Martin T. Freitag
    Jan P. Radtke
    Boris A. Hadaschik
    A. Kopp-Schneider
    Matthias Eder
    Klaus Kopka
    Uwe Haberkorn
    Matthias Roethke
    Heinz-Peter Schlemmer
    Ali Afshar-Oromieh
    [J]. European Journal of Nuclear Medicine and Molecular Imaging, 2016, 43 : 70 - 83
  • [5] Comparison of hybrid 68Ga-PSMA PET/MRI and 68Ga-PSMA PET/CT in the evaluation of lymph node and bone metastases of prostate cancer
    Freitag, Martin T.
    Radtke, Jan P.
    Hadaschik, Boris A.
    Kopp-Schneider, A.
    Eder, Matthias
    Kopka, Klaus
    Haberkorn, Uwe
    Roethke, Matthias
    Schlemmer, Heinz-Peter
    Afshar-Oromieh, Ali
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 (01) : 70 - 83
  • [6] Characterization of bone metastases detected on 68Ga-PSMA PET/CT in newly diagnosed prostate cancer
    Onner, Hasan
    Yilmaz, Farise
    [J]. HELLENIC JOURNAL OF NUCLEAR MEDICINE, 2022, 25 (01) : 57 - 62
  • [7] 68Ga-PSMA PET/CT early detection of Prostate Cancer bone metastases: the end of the osteoblastic era?
    Artigas, C.
    Kamoun, T.
    Garcia, C.
    Wimana, Z.
    Ghanem, G.
    Van Velthoven, R.
    Otte, F.
    Gil, T.
    Flamen, P.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 : S138 - S138
  • [8] 68Ga-PSMA PET/CT for the detection of bone metastases in prostate cancer: a systematic review of the published literature
    Zacho, Helle D.
    Nielsen, Julie B.
    Haberkorn, Uwe
    Stenholt, Louise
    Petersen, Lars J.
    [J]. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, 2018, 38 (06) : 911 - 922
  • [9] 68Ga-PSMA PET/CT in prostate cancer
    Garcia Garzon, J. R.
    de Arcocha Torres, M.
    Delgado-Bolton, R.
    Ceci, F.
    Alvarez Ruiz, S.
    Orcajo Rincon, J.
    Caresia Aroztegui, A. P.
    Garcia Velloso, M. J.
    Garcia Vicente, A. M.
    [J]. REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR, 2018, 37 (02): : 130 - 138
  • [10] LCerebellar Metastases From Prostate Cancer on 68Ga-PSMA PET/CT
    Chan, Mico
    Hsiao, Edward
    Turner, Jennifer
    [J]. CLINICAL NUCLEAR MEDICINE, 2017, 42 (03) : 193 - 194
12345