AIDS - Escape from the immune system

被引：33
|
作者：
Walker, BD [1 ]
Goulder, PJR
机构：
[1] Massachusetts Gen Hosp, Partners AIDS Res Ctr, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA 02114 USA
来源：
NATURE | 2000年 / 407卷 / 6802期
关键词：
D O I：
10.1038/35030283
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Why is the immune system ultimately unable to control HIV infection? Many of the immune system's cytotoxic T lymphocytes detect an HIV-infected cell by its expression of a peptide from the HIV protein Tat. In so doing, the lymphocytes may encourage the evolution of Tat, allowing HIV to escape immune detection.
引用
收藏
页码：313 / 314
页数：2
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