No increased risk for infections with thiopurine-induced leukopenia in inflammatory bowel disease patients without a variant in thiopurine S-methyltransferase

被引：0
|
作者：
Broekman, M. [1 ]
Coenen, M. [2 ]
van Marrewijk, C. [2 ]
Wanten, G. [1 ]
Derijks, L. [3 ]
Vermeulen, S. [2 ,4 ]
Wong, D. [5 ]
Klungel, O. [6 ]
Verbeek, A. [4 ]
Hooymans, P. [5 ]
Scheffer, H. [2 ]
Guchelaar, H. -J. [7 ]
de Jong, D. [1 ]
机构：
[1] Radboud Univ Nijmegen Med Ctr, Dept Gastroenterol, Nijmegen, Netherlands
[2] Radboud Univ Nijmegen Med Ctr, Dept Human Genet, Nijmegen, Netherlands
[3] Maxima Med Ctr Loc Veldhoven, Dept Gastroenterol & Hepatol, Veldhoven, Netherlands
[4] Radboud Univ Nijmegen Med Ctr, Radboud Inst Hlth Sci, Nijmegen, Netherlands
[5] Zuyderland Med Ctr, Dept Clin Pharm Pharmacol & Toxicol, Sittard, Netherlands
[6] Univ Utrecht, Dept Pharmacoepidemiol & Clin Pharmacotherapy, Utrecht, Netherlands
[7] Leiden Univ Med Ctr, Dept Clin Pharm & Toxicol, Leiden, Netherlands
来源：
JOURNAL OF CROHNS & COLITIS | 2016年 / 10卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
P305
引用
收藏
页码：S247 / S247
页数：1
相关论文
共 50 条
  • [1] Early Assessment of Thiopurine Metabolites Identifies Patients at Risk of Thiopurine-induced Leukopenia in Inflammatory Bowel Disease
    Wong, Dennis
    Coenen, Marieke
    Vermeulen, Sita
    Derijks, Luc
    van Marrewijk, Corine
    Klungel, Olaf H.
    Scheffer, Hans
    Franke, Barbara
    Guchelaar, Henk-Jan
    de Jong, Dirk
    Engels, Leopold
    Verbeek, Andr
    Hooymans, Piet
    JOURNAL OF CROHNS & COLITIS, 2017, 11 (02): : 175 - 184
  • [2] NUDT15 polymorphisms are better than thiopurine S-methyltransferase as predictor of risk for thiopurine-induced leukopenia in Chinese patients with Crohn's disease
    Zhu, X.
    Wang, X. -D.
    Chao, K.
    Zhi, M.
    Zheng, H.
    Ruan, H. -L.
    Xin, S.
    Ding, N.
    Hu, P. -J.
    Huang, M.
    Gao, X.
    ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2016, 44 (09) : 967 - 975
  • [3] Influences of Thiopurine Methyltransferase Genotype and Activity on Thiopurine-induced Leukopenia in Korean Patients With Inflammatory Bowel Disease A Retrospective Cohort Study
    Kim, Jae Hak
    Cheon, Jae Hee
    Hong, Seong Soo
    Eun, Chang Soo
    Byeon, Jeong-Sik
    Hong, Sung Yi
    Kim, Bo-Young
    Kwon, Soon-ho
    Kim, Seung Won
    Han, Dong Soo
    Yang, Suk-Kyun
    Kim, Won Ho
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 2010, 44 (10) : E242 - E248
  • [4] Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease
    Dong, Xian-Wen
    Zheng, Qing
    Zhu, Ming-Ming
    Tong, Jing-Lu
    Ran, Zhi-Hua
    WORLD JOURNAL OF GASTROENTEROLOGY, 2010, 16 (25) : 3187 - 3195
  • [5] Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease
    Xian-Wen Dong
    World Journal of Gastroenterology, 2010, 16 (25) : 3187 - 3195
  • [6] Association between Thiopurine S-methyltransferase Polymorphisms and Thiopurine-Induced Adverse Drug Reactions in Patients with Inflammatory Bowel Disease: A Meta-Analysis
    Liu, Yue-Ping
    Wu, Hai-Yan
    Yang, Xiang
    Xu, Han-Qing
    Li, Yong-Chuan
    Shi, Da-Chuan
    Huang, Jun-Fu
    Huang, Qing
    Fu, Wei-Ling
    PLOS ONE, 2015, 10 (03):
  • [7] NUDT15 Variant in Thiopurine-Induced Leukopenia among Malaysian Patients with Inflammatory Bowel Disease
    Wong, Shin Yee
    Lee, Way Seah
    Leow, Hwong Ruey
    Ng, Ruey Terng
    Hilmi, Ida Normiha
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2019, 34 : 157 - 157
  • [8] Thiopurine methyltransferase genotype and thiopurine S-methyltransferase activity in Greek children with inflammatory bowel disease
    Gazouli, Maria
    Pachoula, Ioanna
    Panayotou, Ioanna
    Chouliaras, Georgios
    Anagnou, Nicholas P.
    Chroussos, George
    Roma, Eleftheria
    ANNALS OF GASTROENTEROLOGY, 2012, 25 (03): : 249 - 253
  • [9] Dosing azathioprine in thiopurine S-methyltransferase deficient inflammatory bowel disease patients
    Derijks, L. J. J.
    van Helden, R. B.
    Hommes, D. W.
    Stokkers, P. C.
    GUT, 2008, 57 (06) : 872 - 872
  • [10] Analysis of Thiopurine S-Methyltransferase Genotypes in Japanese Patients with Inflammatory Bowel Disease
    Ban, Hiromitsu
    Andoh, Akira
    Tanaka, Aiko
    Tsujikawa, Tomoyuki
    Sasaki, Masaya
    Saito, Yasuharu
    Fujiyama, Yoshihide
    INTERNAL MEDICINE, 2008, 47 (19) : 1645 - 1648
12345