Tumor mutation burden and efficacy of targeted therapy in patients with EGFR mutant lung cancers.

被引：0
|
作者：
Offin, Michael David [1 ]
Rizvi, Hira [1 ]
Tenet, Megan [1 ]
Ni, Ai [1 ]
Vega, Francisco Sanchez [1 ]
Kris, Mark G. [1 ]
Rudin, Charles M. [1 ]
Riely, Gregory J. [1 ]
Yu, Helena Alexandra [1 ]
Hellmann, Matthew David [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2018年 / 36卷 / 15期
关键词：
D O I：
10.1200/JCO.2018.36.15_suppl.9042
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
9042
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers
    Offin, Michael
    Rizvi, Hira
    Tenet, Megan
    Ni, Andy
    Sanchez-Vega, Francisco
    Li, Bob T.
    Drilon, Alexander
    Kris, Mark G.
    Rudin, Charles M.
    Schultz, Nikolaus
    Arcila, Maria E.
    Ladanyi, Marc
    Riely, Gregory J.
    Yu, Helena
    Hellmann, Matthew D.
    [J]. CLINICAL CANCER RESEARCH, 2019, 25 (03) : 1063 - 1069
  • [2] Tumor Mutation Burden and Efficacy of Molecular Targeted Therapy in Lung Cancer
    Arai, K.
    Sakamoto, T.
    Yamane, K.
    Hirayama, Y.
    Teruya, Y.
    Yanai, M.
    Kinoshita, N.
    Yamaguchi, K.
    Makino, H.
    Kodani, M.
    Igishi, T.
    Yamasaki, A.
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S846 - S847
  • [3] PD-L1 expression, tumor mutation burden and response to immune checkpoint blockade in patients with HER2-mutant lung cancers.
    Lai, Wei-Chu Victoria
    Feldman, Daniel L.
    Buonocore, Darren J.
    Brzostowski, Edyta B.
    Rizvi, Hira
    Plodkowski, Andrew J.
    Ni, Ai
    Sabari, Joshua K.
    Offin, Michael David
    Kris, Mark G.
    Drilon, Alexander E.
    Arcila, Maria E.
    Hellmann, Matthew David
    Li, Bob T.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [4] Characterization of tumor mutation burden (TMB) in gastrointestinal (GI) cancers.
    Salem, Mohamed E.
    Xiu, Joanne
    Weinberg, Benjamin Adam
    El-Deiry, Wafik S.
    Weiner, Louis M.
    Gatalica, Zoran
    Liu, Zhuqing
    El Ghazaly, Hesham
    Xiao, Nianqing
    Hwang, Jimmy J.
    Philip, Philip Agop
    Shields, Anthony Frank
    Lenz, Heinz-Josef
    Marshall, John
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
  • [5] Targeted therapy-induced senescence enhances immune surveillance of KRAS mutant lung cancers.
    Ruscetti, Marcus
    Leibold, Josef
    Bott, Matthew J.
    Shields, Mario
    Chen, Chi-Chao
    Fennell, Myles
    Chen, Ho-Chung
    Baslan, Timour
    Salgado, Nelson R.
    Manchado, Eusebio
    Low, Vivien
    Poirier, John T.
    Rudin, Charles M.
    de Stanchina, Elisa
    Egeblad, Mikala
    Sherr, Charles J.
    Lowe, Scott W.
    [J]. CANCER RESEARCH, 2018, 78 (10) : 51 - 52
  • [6] THE EFFICACY OF ROUTINE EGFR MUTATION TESTING OF LUNG CANCERS
    Metcalf, C.
    Bentel, J. M.
    Thomas, M. A.
    Sadowska, A.
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2012, 7 (09) : S177 - S177
  • [7] Improving Therapy for EGFR-Mutant Lung Cancers
    Piotrowska, Zofia
    [J]. ONCOLOGIST, 2017, 22 : S4 - S4
  • [8] A phase 1 study of osimertinib and bevacizumab as initial treatment for patients with EGFR-mutant lung cancers.
    Yu, Helena Alexandra
    Hayes, Sara A.
    Young, Robert J.
    Ni, Ai
    Rodriguez, Christopher
    Makhnin, Alex
    Riely, Gregory J.
    Kris, Mark G.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [9] Increased neutrophil infiltration and lower prevalence of tumor mutation burden and microsatellite instability are hallmarks of RAS mutant colorectal cancers.
    Lou, Emil
    Baca, Yasmine
    Xiu, Joanne
    Nelson, Andrew
    Subramanian, Subbaya
    Salem, Mohamed E.
    Beg, Muhammad Shaalan
    Fontana, Elisa
    Diab, Maria
    Philip, Agop Philip
    Goldberg, Richard M.
    Pandey, Ritu
    Arkenau, Tobias
    Sun, Weijing
    Lenz, Heinz-Josef
    Shields, Anthony Frank
    El-Deiry, Wafik S.
    Korn, Wolfgang Michael
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [10] High Tumor Mutation Burden Is Associated with Poor Clinical Outcome in EGFR-Mutated Lung Adenocarcinomas Treated with Targeted Therapy
    Sung, Ji-Youn
    Park, Dong-Won
    Lee, Seung-Hyeun
    [J]. BIOMEDICINES, 2022, 10 (09)
12345