Survival after dementia diagnosis in five racial/ethnic groups

被引:69
|
作者
Mayeda, Elizabeth R. [1 ]
Glymour, M. Maria [1 ]
Quesenberry, Charles P. [2 ]
Johnson, Julene K. [3 ,4 ]
Perez-Stable, Eliseo J. [5 ]
Whitmer, Rachel A. [1 ,2 ]
机构
[1] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
[2] Kaiser Permanente Div Res, Oakland, CA USA
[3] Univ Calif San Francisco, Inst Hlth & Aging, San Francisco, CA USA
[4] Univ Calif San Francisco, Ctr Aging Diverse Communities, San Francisco, CA 94143 USA
[5] Natl Inst Minor Hlth & Hlth Dispar, Off Director, NIH, Bethesda, MD USA
基金
美国国家卫生研究院;
关键词
Dementia; Survival; Mortality; Race; Ethnicity; Disparities; Cohort; Epidemiology; MILD COGNITIVE IMPAIRMENT; ALZHEIMERS-DISEASE; AFRICAN-AMERICANS; OLDER PATIENTS; INCREASED RISK; MORTALITY; HEALTH; ASSOCIATION; DEPRESSION; PLACEMENT;
D O I
10.1016/j.jalz.2016.12.008
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: Information on anticipated survival time after dementia diagnosis among racially/ethnically diverse patients is needed to plan for care and evaluate disparities. Methods: Dementia-free health care members aged >= 64 years were followed (1/1/2000-12/31/2013) for dementia diagnosis and subsequent survival (n = 23,032 Asian American; n = 18,778 African American; n = 21,000 Latino; n = 4543 American Indian/Alaska Native; n = 206,490 white). Kaplan-Meier curves were estimated for survival after dementia diagnosis by race/ethnicity. We contrasted mortality patterns among people with versus without dementia using Cox proportional hazards models. Results: After dementia diagnosis (n = 59,494), whites had shortest median survival (3.1 years), followed by American Indian/Alaska Natives (3.4 years), African Americans (3.7 years), Latinos (4.1 years), and Asian Americans (4.4 years). Longer postdiagnosis survival among racial/ethnic minorities compared with whites persisted after adjustment for comorbidities. Racial/ethnic mortality inequalities among dementia patients mostly paralleled mortality inequalities among people without dementia. Discussion: Survival after dementia diagnosis differs by race/ethnicity, with shortest survival among whites and longest among Asian Americans. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:761 / 769
页数:9
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