Enhanced killing of glioblastoma cells by HSV-1 vector mediated combined IκBα mutant and HSV-TK expression under GCV administration

被引：0
|
作者：
Moriuchi, S
Yamasaki, M
Yoshimine, T
Wolf, D
Huang, SH
Cohen, J
Glorioso, JC
机构：
[1] Osaka Natl Hosp, Osaka, Japan
[2] Osaka Grad Univ, Sch Med, Suita, Osaka, Japan
[3] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
来源：
MOLECULAR THERAPY | 2003年 / 7卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
741
引用
收藏
页码：S286 / S287
页数：2
相关论文
共 9 条
  • [1] Effective treatment of experimental glioblastoma by HSV vector-mediated TNFα and HSV-tk gene transfer in combination with radiosurgery and ganciclovir administration
    Niranjan, A
    Moriuchi, S
    Lunsford, LD
    Kondziolka, D
    Flickinger, JC
    Fellows, W
    Rajendiran, S
    Tamura, M
    Cohen, JB
    Glorioso, JC
    MOLECULAR THERAPY, 2000, 2 (02) : 114 - 120
  • [2] The selective killing effect of adenoviral mediated HSV-tk/GCV suicide gene system controlled by hTERT promoter on bladder cancer cells
    王亚轩
    China Medical Abstracts, 2005, (03) : 201 - 202
  • [3] Quantitative kinetics of HSV-1-tk gene delivery to tumor cells using a recombinant HSV-1 vector:: Implications for imaging HSV-1 mediated gene transfer in vivo
    Jacobs, AH
    Tjuvajev, JG
    Joshi, A
    Joshi, R
    Herrlinger, U
    Balatoni, J
    Finn, R
    Breakefield, XO
    Blasberg, RG
    NEUROLOGY, 1998, 50 (04) : A273 - A273
  • [4] I kappa B-mediated apoptotic gene therapy against acute myelogenous leukemia using replication defective HSV-1 vector expressing TK and mutant I kappa B alpha
    Kuwayama, Y
    Suzuki, T
    Moriuchi, S
    Glorioso, JC
    Bessho, M
    CELLULAR AND MOLECULAR BIOLOGY, 2005, 51 (01) : 77 - 86
  • [5] Combination gene therapy for glioblastoma involving herpes simplex virus (HSV) vector-mediated co-delivery of mutant IκBα and HSV thymidine kinase against glioblastoma
    Moriuchi, Shusuke
    Glorioso, Joseph C.
    Maruno, Motohiko
    Izumoto, Shuichi
    Yoshimine, Toshiki
    JOURNAL OF NEUROIMMUNOLOGY, 2006, 178 : 49 - 49
  • [6] Combination gene therapy for glioblastoma involving herpes simplex virus vector-mediated codelivery of mutant IκBα and HSV thymidine kinase
    Moriuchi, S
    Glorioso, JC
    Maruno, M
    Izumoto, S
    Wolfe, D
    Huang, SH
    Cohen, JB
    Yoshimine, T
    CANCER GENE THERAPY, 2005, 12 (05) : 487 - 496
  • [7] Combination gene therapy for glioblastoma involving herpes simplex virus vector-mediated codelivery of mutant IκBα and HSV thymidine kinase
    Shusuke Moriuchi
    Joseph C Glorioso
    Motohiko Maruno
    Shuichi Izumoto
    Darren Wolfe
    Shaohua Huang
    Justus B Cohen
    Toshiki Yoshimine
    Cancer Gene Therapy, 2005, 12 : 487 - 496
  • [8] Monitoring HSV-1-tk and lacZ gene delivery and co-expression by a replication-conditional HSV-1 vector in 9L gliosarcoma cells:: Implications for therapeutic gene imaging in vivo.
    Jacobs, A
    Tjuvajev, JG
    Joshi, R
    Herrlinger, U
    Balatoni, J
    Finn, R
    Breakefield, XO
    Blasberg, RG
    JOURNAL OF NUCLEAR MEDICINE, 1998, 39 (05) : 236P - 236P
  • [9] A phase I study of intralesional administration of an adenovirus vector expressing the HSV-1 thymidine kinase gene (AdV.RSV-TK) in combination with escalating doses of ganciclovir in patients with cutaneous metastatic malignant melanoma
    Morris, JC
    Ramsey, WJ
    Wildner, O
    Muslow, HA
    Aguilar-Cordova, E
    Blaese, RM
    HUMAN GENE THERAPY, 2000, 11 (03) : 487 - 503
1