Nanoceria exhibit redox state-dependent catalase mimetic activity

被引:880
|
作者
Pirmohamed, Talib [1 ]
Dowding, Janet M. [1 ]
Singh, Sanjay [1 ]
Wasserman, Brian [1 ]
Heckert, Eric [1 ]
Karakoti, Ajay S. [2 ,3 ]
King, Jessica E. S. [2 ,3 ]
Seal, Sudipta [2 ,3 ]
Self, William T. [1 ]
机构
[1] Burnett Sch Biomed Sci, Orlando, FL USA
[2] Univ Cent Florida, Mech Mat & Aerosp Engn Nanosci & Technol Ctr, Orlando, FL 32816 USA
[3] Univ Cent Florida, Adv Mat Proc & Anal Ctr, Orlando, FL 32816 USA
关键词
SUPEROXIDE-DISMUTASE; OXIDE NANOPARTICLES; OXIDATIVE STRESS; CERIUM; NANOSTRUCTURES;
D O I
10.1039/b922024k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this study we have found that cerium oxide nanoparticles exhibit catalase mimetic activity. Surprisingly, the catalase mimetic activity correlates with a reduced level of cerium in the +3 state, in contrast to the relationship between surface charge and superoxide scavenging properties.
引用
收藏
页码:2736 / 2738
页数:3
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