Poststernotomy sternal osteomyelitis and mediastinitis by Trichosporon asahii: a rare occurrence with a grave prognosis

被引：4

作者：

Baraboutis, Ioannis ^{[1
]}

Belesiotou, Elina ^{[2
]}

Platsouka, Evaggelia ^{[2
]}

Papastamopoulos, Vassilios ^{[1
]}

Mentzelopoulos, Spyridon ^{[3
]}

Nanas, Serafeim ^{[3
]}

Argyropoulou, Athena ^{[2
]}

Paniara, Olga ^{[2
]}

Skoutelis, Athanasios ^{[1
]}

机构：

[1] Evaggelismos Gen Hosp, Dept Internal Med 5, Div Infect Dis, Athens 10676, Greece

[2] Evaggelismos Gen Hosp, Dept Microbiol, Athens 10676, Greece

[3] Evaggelismos Gen Hosp, Intens Care Unit, Athens, Greece

来源：

MYCOSES | 2010年 / 53卷 / 03期

关键词：

D O I：

10.1111/j.1439-0507.2009.01709.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

P>Post-sternotomy infectious complications, including superficial and deep wound infections, sternal osteomyelitis and mediastinitis, are rarely caused by fungi. Trichosporon asahii is the main Trichosporon species that causes systemic infection in humans. Most cases involved neutropenic patients with hematologic malignancies. We report a unique case of a non-cancer, non-neutropenic but severely ill patient who developed an ultimately lethal T. asahii infection after sternotomy. We speculate that our patient had been colonized with the fungus and his surgical site infection may have been related to his emergency revascularization surgery. Therapy with liposomal amphotericin failed to sterilize the bloodstream despite in vitro susceptibility results. The addition of voriconazole helped sterilizing the bloodstream without changing the outcome. Physicians must be aware of the continuously expanding spectrum of infections with this emerging difficult-to-treat fungal pathogen.

引用

页码：272 / 274

页数：3