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Univ Nacl Sur, CONICET, Dept Biol Bioquim & Farm, Inst Invest Biol & Biomed Sur INBIOSUR,Lab Toxico, San Juan 670, RA-8000 Bahia Blanca, Buenos Aires, Argentina Univ Nacl Sur, CONICET, Dept Biol Bioquim & Farm, Inst Invest Biol & Biomed Sur INBIOSUR,Lab Toxico, San Juan 670, RA-8000 Bahia Blanca, Buenos Aires, Argentina