Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk

被引：5

作者：

Berardi, Alberto ^{[1
,6
]}

Tzialla, Chryssoula ^{[2
]}

Travan, Laura ^{[3
]}

Bua, Jenny ^{[3
]}

Santori, Daniele ^{[4
]}

Azzalli, Milena ^{[5
]}

Spada, Caterina ^{[6
]}

Lucaccioni, Laura ^{[1
]}

Memo, L. ^{[7
]}

Nicolini, G. ^{[7
]}

Ciccia, M. ^{[8
]}

Bastelli, A. ^{[8
]}

Sandri, F. ^{[8
]}

Ambretti, S. ^{[9
]}

Capretti, M. G. ^{[9
]}

Corvaglia, L. ^{[9
]}

Dondi, A. ^{[9
]}

Lanari, M. ^{[9
]}

Pasini, L. ^{[9
]}

Ragni, L. ^{[9
]}

Albarelli, A. ^{[10
]}

Fiorini, V. ^{[11
]}

Giugno, C. ^{[11
]}

Lanzoni, P. ^{[11
]}

Di Grande, E. ^{[12
]}

Polese, A. ^{[12
]}

China, M. C. ^{[13
]}

Rizzo, V. ^{[13
]}

Stella, M. ^{[13
]}

Zucchini, A. ^{[14
]}

Malaguti, L. ^{[15
]}

Garani, G. ^{[16
]}

Lama, C. ^{[16
]}

Nasi, S. ^{[17
]}

Bacchini, P. ^{[17
]}

Fragni, G. ^{[17
]}

Baldassarri, P. ^{[18
]}

Pulvirenti, R. M. ^{[18
]}

Valletta, E. ^{[18
]}

Venturoli, V. ^{[18
]}

Alessandrini, C. ^{[19
]}

Bidetti, M. L. ^{[19
]}

Incerti, S. Storchi ^{[19
]}

Di Carlo, C. ^{[20
]}

Lanzoni, A. ^{[20
]}

Serra, L. ^{[20
]}

Silvestrini, D. ^{[20
]}

Facchinetti, F. ^{[21
]}

Ferrari, F. ^{[21
]}

Lugli, L. ^{[21
]}

机构：

[1] Azienda Osped Univ Policlin, Dipartimento Integrato Materno Infantile, Unita Operat Terapia Intens Neonatale, Modena, Italy

[2] Fdn IRCCS Policlin San Matteo, Patol Neonatale & Terapia Intens Neonatale, Neonatol, Pavia, Italy

[3] IRCCS Burlo Garofolo, Unita Operat Terapia Intens Neonatale, Trieste, Italy

[4] Azienda Osped Santa Maria Angeli, Struttura Complessa Pediat & Neonatol, Pordenone, Italy

[5] Osped S Anna Ferrara, Unita Operat Terapia Intens Neonatale, Ferrara, Italy

[6] Univ Modena & Reggio Emilia, Azienda Osped Univ Policlin, Scuola Specializzaz Pediat, Via Pozzo 71, I-41124 Modena, MO, Italy

[7] Osped San Martino, Belluno, Italy

[8] Osped Maggiore Bologna, Bologna, Italy

[9] Policlin Sant Orsola, Bologna, Italy

[10] Osped Santa Maria, Borgo Taro, Italy

[11] Osped B Ramazzini, Carpi, Italy

[12] Osped Sant Anna, Castelnuovo Ne Monti, Italy

[13] Osped Gen Provinciale M Bufalini, Cesena, Italy

[14] Osped Civile, Faenza, Italy

[15] Osped Delta, Ferrara, Italy

[16] Osped Sant Anna, Ferrara, Italy

[17] Osped Vaio, Fidenza, Italy

[18] Osped Morgagni Pieratoni, Forli, Italy

[19] Osped Civile, Guastalla, Italy

[20] Osped Santa Maria Scaletta, Imola, Italy

[21] Azienda Osped Policlin, Modena, Italy

[22] Osped Baggiovara, Modena, Italy

[23] Osped Franchini, Montecchio Emilia, Italy

[24] Osped Policlin, Parma, Italy

[25] Osped Civile, Pavullo nel Frignano, Italy

[26] Osped G Saliceto, Piacenza, Italy

[27] Lab Area Vasta Emilia Romagna, Pievesestina, Italy

[28] Osped Santa Maria Croci, Ravenna, Italy

[29] Osped Santa Maria Nuova, Reggio Emilia, Italy

[30] Osped Infermi, Rimini, Italy

[31] Osped Civile, Sassuolo, Italy

[32] Osped C Magati, Scandiano, Italy

来源：

ITALIAN JOURNAL OF PEDIATRICS | 2018年 / 44卷

关键词：

Group B streptococcus; Neonatal sepsis; Intrapartum antibiotic prophylaxis; Newborn infant; Risk factors; Prevention; GROUP-B STREPTOCOCCUS; PHYSICAL-EXAMINATION; MANAGEMENT;

D O I：

10.1186/s13052-018-0515-8

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus regarding this issue. A strategy for managing neonates, entirely based on serial physical examinations, has been developed in two Italian regions. This strategy seems safe, while reducing laboratory tests and unnecessary antibiotics. In the current commentary we provide area-based data concerning the prevention of EOS in 2 northern Italian regions, and we detail the results of their strategy for managing healthy-appearing newborns at risk for EOS.

引用

页数：4

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