Covalent Attachment of Polymersomes to Surfaces

被引：22
|
作者：
Domes, Stephanie [1 ]
Filiz, Volkan [1 ]
Nitsche, Jasmin [1 ]
Froemsdorf, Andreas [1 ]
Foerster, Stephan [1 ]
机构：
[1] Univ Hamburg, Inst Phys Chem, D-20146 Hamburg, Germany
来源：
LANGMUIR | 2010年 / 26卷 / 10期
关键词：
BLOCK-COPOLYMERS; VESICLES; LIPOSOMES; MICELLES; ADHESION; DELIVERY;
D O I：
10.1021/la904175u
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We show that vesicles made of block copolymers with aldehyde end groups can be covalently attached to aminated and non-aminated, untreated glass surfaces. The attached vesicles were sufficiently stable to allow a detailed in of vesicle shapes by confocal laser scanning microscopy (CLSM) and A FM in aqueous solutions allowing reconstruction of 3D images of the vesicle structure. Covalently attached PCL-PEO, PLA-PEO, and PI-PEO block copolymer vesicles have different footprint areas and different shapes due to their differences in bilayer stiffness.
引用
收藏
页码：6927 / 6931
页数：5
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