HMR1392:: In vivo anti-resorptive activity of a new high affinity nonpeptide α-v β3 integrin ligand.

被引：0

作者：

Doucet, B

Auberval, M

Gourvest, J

Bouali, Y

Da Ponte, F

Lepescheux, L

Bardelay, C

Bouchoux, F

Viet, S

Peyman, A

Gadek, T

Bodary, S

Gaillard, M

Baron, R

机构：

[1] Hoechst Marion Roussel, Romainville, France

[2] Hoechst Marion Roussel, Frankfurt, Germany

[3] Genetec Inc, San Francisco, CA USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2000年 / 15卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

SU257

引用

页码：S393 / S393

页数：1

共 13 条

[1] Identification of alpha-v beta-3 integrin antagonists with anti-resorptive activity.
Kimmel, DB
Rodan, SB
Duggan, ME
Hartman, G
Coleman, PJ
Brashear, K
Leu, CT
Wesolowski, G
Prueksaritanont, T
Gentile, MA
Seedor, JG
Pennypacker, B
Masarachia, P
Duong, LT
Lipfert, L
Rodan, GA
JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 : S352 - S352
[2] Structure-based design of a novel, osteoclast-selective, nonpeptide Src SH2 inhibitor with in vivo anti-resorptive activity.
Sawyer, T
Shakespeare, W
Yang, M
Bohacek, R
Cerasoli, F
Stebbins, K
Sundaramoorthi, R
Vu, C
Pradeepan, S
Metcalf, C
Haraldson, C
Merry, T
Dalgarno, D
Hatada, M
van Schravendijk, M
Violette, S
Smith, J
Guan, W
Bartlett, C
Iuliucci, J
Weigele, M
JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 : S516 - S516
[3] A high affinity non-peptide αvβ3 integrin ligand inhibits bone resorption in vitro and in vivo.
Rodan, SB
Duggan, ME
Fisher, JE
Hamill, T
Hartman, GD
Ihle, N
Leu, CT
Nagy, RM
Perkins, JJ
Wesolowski, G
JOURNAL OF BONE AND MINERAL RESEARCH, 1999, 14 : S246 - S246
[4] A high affinity non-peptide alpha(v)beta(3) ligand inhibits osteoclast activity in vitro and in vivo.
Rodan, SB
Duong, L
Fisher, JE
Gentile, M
Leu, CT
Nagy, RM
Wesolowski, G
Duggan, M
Hoffman, WF
Ihle, NC
Whitman, DB
Rodan, GA
JOURNAL OF BONE AND MINERAL RESEARCH, 1996, 11 : M430 - M430
[5] Design, Synthesis and Anti-Melanoma Activity of Novel Annexin V Derivative with β3-Integrin Affinity
Zhu, Jingyi
Li, Wenjuan
Jing, Jian
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (13)
[6] Transmembrane-truncated αvβ3 integrin retains high affinity for ligand binding:: evidence for an 'inside-out' suppressor?
Mehta, RJ
Diefenbach, B
Brown, A
Cullen, E
Jonczyk, A
Güssow, D
Luckenbach, GA
Goodman, SL
BIOCHEMICAL JOURNAL, 1998, 330 : 861 - 869
[7] Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors
Xiao, Wenwu
Li, Tianhong
Bononi, Fernanda C.
Lac, Diana
Kekessie, Ivy A.
Liu, Yanlei
Sanchez, Eduardo
Mazloom, Anisha
Ma, Ai-hong
Lin, Jia
Tran, Jimmy
Yang, Kevin
Lam, Kit S.
Liu, Ruiwu
EJNMMI RESEARCH, 2016, 6 : 1 - 12
[8] Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors
Wenwu Xiao
Tianhong Li
Fernanda C. Bononi
Diana Lac
Ivy A. Kekessie
Yanlei Liu
Eduardo Sanchez
Anisha Mazloom
Ai-hong Ma
Jia Lin
Jimmy Tran
Kevin Yang
Kit S. Lam
Ruiwu Liu
EJNMMI Research, 6
[9] High-Affinity αvβ3 Integrin Targeted Optical Probe as a New Imaging Biomarker for Early Atherosclerosis: Initial Studies in Watanabe Rabbits
Julie Heroux
Ahmed M. Gharib
Narasimhan S. Danthi
Sylvain Cecchini
Jacques Ohayon
Roderic I. Pettigrew
Molecular Imaging and Biology, 2010, 12 : 2 - 8
[10] High-Affinity αvβ3 Integrin Targeted Optical Probe as a New Imaging Biomarker for Early Atherosclerosis: Initial Studies in Watanabe Rabbits
Heroux, Julie
Gharib, Ahmed M.
Danthi, Narasimhan S.
Cecchini, Sylvain
Ohayon, Jacques
Pettigrew, Roderic I.
MOLECULAR IMAGING AND BIOLOGY, 2010, 12 (01) : 2 - 8

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