Most previous studies on the association between moisture damage and asthma have been cross-sectional and relied on self-reported exposure and health. The present authors studied the association by carrying out careful home inspections among new, clinically determined cases of asthma and controls. New cases of asthma aged 12-84 months (n=121) were recruited prospectively and matched for year of birth, sex and living area with two randomly selected population controls (n=241). Trained engineers visited all homes. Both cases and controls had lived >= 75% of their lifetime or the past 2 yrs; in their current home. Risk of asthma increased with severity of moisture damage and presence of visible mould in the main living quarters but not in other areas of the house. Cases more often had damage in their bedroom. Associations were comparable for atopic and nonatopic asthma and for children aged > 30 months or <= 30 months. The present results, using standardised assessment of exposure and asthma, suggest that moisture damage and mould growth in the main living quarters are associated with the development of asthma in early childhood.
机构:
Mayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Soonchunhyang Univ, Dept Internal Med, Div Cardiol, Seoul, South KoreaMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Bang, Duk Won
Wi, Chung-Il
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Mayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Wi, Chung-Il
Kim, Eun Na
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Mayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Soonchunhyang Univ, Dept Internal Med, Div Nephrol, Seoul, South KoreaMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Kim, Eun Na
Hagan, John
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Mayo Clin, Dept Internal Med, Div Allerg Dis, Rochester, MN USAMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Hagan, John
Roger, Veronique
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Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
Mayo Clin, Dept Internal Med, Div Cardiovasc Dis, Rochester, MN USAMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Roger, Veronique
Manemann, Sheila
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Mayo Clin, Dept Hlth Sci Res, Rochester, MN USAMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Manemann, Sheila
Lahr, Brian
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Mayo Clin, Dept Hlth Sci Res, Rochester, MN USAMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Lahr, Brian
Ryu, Euijung
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Mayo Clin, Dept Hlth Sci Res, Rochester, MN USAMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Ryu, Euijung
Juhn, Young J.
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Mayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Mayo Clin, Dept Internal Med, Rochester, MN USAMayo Clin, Dept Pediat & Adolescent Med, 200 First St SW, Rochester, MN 55905 USA
Juhn, Young J.
[J].
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE,
2016,
4
(05):
: 917
-
923
机构:
Univ New Mexico, Pediat Neurol, Albuquerque, NM 87131 USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Kaur, Harsheen
Lachance, Daniel H.
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Mayo Clin, Neurol, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Lachance, Daniel H.
Ryan, Conor S.
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机构:
Mayo Clin, Child & Adolescent Neurol, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Ryan, Conor S.
Sheen, Youn Ho
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h-index: 0
机构:
CHA Gangnam Med Ctr, Pediat, Seoul, South Korea
Mayo Clin, Pediat & Adolescent Med, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Sheen, Youn Ho
Seol, Hee Yun
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Mayo Clin, Pediat & Adolescent Med, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Seol, Hee Yun
Wi, Chung-Il
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Mayo Clin, Pediat & Adolescent Med, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Wi, Chung-Il
Sohn, Sunghwan
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Mayo Clin, Biomed Stat & Informat, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Sohn, Sunghwan
King, Katherine S.
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Mayo Clin, Biomed Stat & Informat, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
King, Katherine S.
Ryu, Euijung
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h-index: 0
机构:
Mayo Clin, Hlth Sci Res, Rochester, MN USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA
Ryu, Euijung
Juhn, Young
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Community Pediat & Adolescent Med, Rochester, MN 55905 USAUniv New Mexico, Pediat Neurol, Albuquerque, NM 87131 USA