Dyslipidemias in renal diseases: pathogenesis and treatment

Patients with renal diseases like nephrotic syndrome, chronic renal failure (uremia) and renal transplantation frequently present disturbances of lipid metabolisms, however their pathogenesis is partially understood. Moreover, cardiovascular diseases are responsible for many deaths in these patients. Although the effect of the dyslipidemias in the development of atherosclerosis in renal diseases is not clear, they probably play a role. Since actually the survival of these patients is substantial, it is important to manage them appropriately with regard to their dyslipidemias. This review will examine the pathogenesis and treatment of dyslipidemias in patients with nephrotic syndrome, chronic renal failure and renal transplantation.