Microglia P2X4 receptors as pharmacological targets for demyelinating diseases

被引：12
|
作者：
Di Virgilio, Francesco [1 ]
Sarti, Alba Clara [1 ]
机构：
[1] Univ Ferrara, Dept Morphol Surg & Expt Med, Ferrara, Italy
来源：
EMBO MOLECULAR MEDICINE | 2018年 / 10卷 / 08期
关键词：
P2X(4); MACROPHAGES; PHYSIOLOGY; ATP;
D O I：
10.15252/emmm.201809369
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis.
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收藏
页数：3
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