Heme-NO complex formation inhibits NO synthase dimer assembly

被引:0
|
作者
Chen, Y [1 ]
Stuehr, DJ [1 ]
机构
[1] Cleveland Clin Fdn, Dept Immunol, Cleveland, OH 44195 USA
来源
FASEB JOURNAL | 1997年 / 11卷 / 09期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
P92
引用
收藏
页码:A787 / A787
页数:1
相关论文
共 50 条
  • [1] HEME-NO COMPLEX-FORMATION IN NEURONAL NO SYNTHASE DURING STEADY-STATE CATALYSIS
    ABUSOUD, HM
    WANG, J
    ROUSSEAU, DL
    FUKUTO, JM
    IGNARRO, LJ
    STUEHR, DJ
    FASEB JOURNAL, 1995, 9 (06): : A1488 - A1488
  • [2] Chimeras of nitric-oxide synthase types I and III establish fundamental correlates between heme reduction, heme-NO complex formation, and catalytic activity
    Adak, S
    Aulak, KS
    Stuehr, DJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (26) : 23246 - 23252
  • [3] Control of nitric oxide synthase dimer assembly by a heme-NO-dependent mechanism
    Chen, YS
    Panda, K
    Stuehr, DJ
    BIOCHEMISTRY, 2002, 41 (14) : 4618 - 4625
  • [4] Regulation of the properties of the heme-NO complexes in nitric-oxide synthase by hydrogen bonding to the proximal cysteine
    Couture, M
    Adak, S
    Stuehr, DJ
    Rousseau, DL
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (41) : 38280 - 38288
  • [5] How does a valine residue that modulates heme-NO binding kinetics in inducible NO synthase regulate enzyme catalysis?
    Wang, Zhi-Qiang
    Wei, Chin-Chuan
    Stuehr, Dennis J.
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2010, 104 (03) : 349 - 356
  • [6] GPIbα dimer formation and cell surface expression:: A filamin binding domain is essential for dimer formation but not for assembly of a GPIb/IX complex
    Kanaji, T
    Hamasaki, N
    Izuhara, K
    Ware, J
    BLOOD, 2004, 104 (11) : 434A - 434A
  • [7] Surface Residue Glu762 of the FMN Subdomain Impacts Ferrous Heme-NO reactivity in Neuronal Nitric Oxide Synthase
    Haque, Mohammad Mahfuzul
    Wang, Zhi-Qiang
    Fadlalla, Mohammed
    Stuehr, Dennis J.
    FASEB JOURNAL, 2009, 23
  • [8] Antifungal imidazoles block assembly of inducible NO synthase into an active dimer
    Sennequier, N
    Wolan, D
    Stuehr, DJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (02) : 930 - 938
  • [9] Structure of a loose dimer: an intermediate in nitric oxide synthase assembly
    Pant, K
    Crane, BR
    JOURNAL OF MOLECULAR BIOLOGY, 2005, 352 (04) : 932 - 940
  • [10] Assembly and activation of heme-deficient neuronal NO synthase with various porphyrins
    Bender, AT
    Kamada, Y
    Kleaveland, PA
    Osawa, Y
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2002, 91 (04) : 625 - 634