A metal-free catalytic system for the oxidation of benzylic methylenes and primary amines under solvent-free conditions

被引：121
|
作者：
Zhang, Jintang
Wang, Zhentao
Wang, Ye
Wan, Changfeng
Zheng, Xiaoqi [1 ]
Wang, Zhiyong
机构：
[1] Univ Sci & Technol China, Joint Lab Green Synthet Chem, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Peoples R China
来源：
GREEN CHEMISTRY | 2009年 / 11卷 / 12期
关键词：
TERT-BUTYL HYDROPEROXIDE; PRIMARY ALIPHATIC-AMINES; SELECTIVE OXIDATION; AEROBIC OXIDATION; SATURATED-HYDROCARBONS; CORRESPONDING NITRILES; RUTHENIUM HYDROXIDE; MEDIATED OXIDATION; MOLECULAR-IODINE; PRIMARY ALCOHOLS;
D O I：
10.1039/b919346b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Iodine-pyridine-tert-butylhydroperoxide is developed as a green and efficient catalytic system for the oxidation of benzylic methylenes to ketones and primary amines to nitriles. The reaction conditions are quite mild and environmentally benign, no transition metals, organic solvents or hazard reagents being needed. The oxidation of benzylic methylenes gave the corresponding ketones in excellent yields with complete chemoselectivity, while the oxidation of primary amines was complete in several minutes, affording various nitriles in moderate to good yields.
引用
收藏
页码：1973 / 1978
页数：6
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