Advanced polymer-based composites and structures for biomedical applications

被引:63
|
作者
Guo, Zhengchao [1 ]
Poot, Andre A. [1 ]
Grijpma, Dirk W. [1 ]
机构
[1] Univ Twente, Fac Sci & Technol, Dept Biomat Sci & Technol, Enschede, Netherlands
关键词
Polymer-based composites; Biomedical application; Tissue engineering; Bioactive composites; Non-bioactive composites; Additive manufacturing; 3D printing; Stereolithography; Electrospinning; Microfabrication; Biomedical devices; IN-VITRO DEGRADATION; POLY(TRIMETHYLENE CARBONATE); REGENERATIVE MEDICINE; POROUS SCAFFOLDS; ANTIBACTERIAL ACTIVITY; CONDUCTIVE POLYMERS; CURRENT CHALLENGES; TISSUE; BIOMATERIALS; NANOPARTICLES;
D O I
10.1016/j.eurpolymj.2021.110388
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
A fast increasing demand of medical products based on biomaterials and tissue engineering has led to an extensive growth in biomedical research in the past two decades. A highly interesting class of biomaterials are polymer-based composites, which nowadays are widely used in biomedical applications due to their outstanding physical and mechanical properties. In this paper, we aim to summarize the advancement in polymer-based composites with regard to their properties, structure and fabrication using different techniques. Bioactive polymer-based composites, such as bone-forming, electrically conductive, magnetic, bactericidal and oxygen-releasing materials, as well as non-bioactive polymer-based composites containing reinforcing fillers and porogens are discussed. Amongst others, scaffold structures fabricated by particle leaching, electrospinning and additive manufacturing are described. In each section, significant and recent advances of polymer-based composites in biomedical applications are addressed.
引用
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页数:13
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