The biology and evolution of transposable elements in parasites

被引：21

作者：

Carmen Thomas, M. ^{[1
]}

Macias, Francisco ^{[1
]}

Alonso, Carlos ^{[2
]}

Lopez, Manuel C. ^{[1
]}

机构：

[1] CSIC, Inst Parasitol & Biomed Lopez Neyra, Dept Biol Mol, Granada 18100, Spain

[2] CSIC, Ctr Biol Mol Severo Ochoa, Madrid, Spain

来源：

TRENDS IN PARASITOLOGY | 2010年 / 26卷 / 07期

关键词：

NON-LTR RETROTRANSPOSONS; HUMAN BLOOD FLUKE; TERMINAL REPEAT RETROTRANSPOSON; MOBILE GENETIC ELEMENTS; TRYPANOSOMA-CRUZI CODES; SCHISTOSOMA-MANSONI; DNA TRANSPOSONS; REVERSE-TRANSCRIPTASE; ENTAMOEBA-HISTOLYTICA; L1TC RETROTRANSPOSON;

D O I：

10.1016/j.pt.2010.04.001

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Transposable elements (TEs) are dynamic elements that can reshape host genomes by generating rearrangements with the potential to create or disrupt genes, to shuffle existing genes, and to modulate their patterns of expression. In the genomes of parasites that infect mammals several TEs have been identified that probably have been maintained throughout evolution due to their contribution to gene function and regulation of gene expression. This review addresses how TEs are organized, how they colonize the genomes of mammalian parasites, the functional role these elements play in parasite biology, and the interactions between these elements and the parasite genome.

引用

页码：350 / 362

页数：13

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