PHYTOTOXIC SECONDARY METABOLITES FROM THE ENDOLICHENIC FUNGUS Myxotrichum sp.

被引：4
|
作者：
Yuan, Chao [1 ,2 ]
Ding, Gang [3 ,4 ]
Wang, Haiying [5 ]
Guo, Yuhua [3 ,4 ]
Ma, Xiaojun [3 ,4 ]
Zou, Zhongmei [3 ,4 ]
机构：
[1] Chinese Acad Med Sci, Inst Med Plant Dev, Yunnan Branch, Jinghong 666100, Peoples R China
[2] Peking Union Med Coll, Jinghong 666100, Peoples R China
[3] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China
[4] Peking Union Med Coll, Beijing 100193, Peoples R China
[5] Shandong Normal Univ, Coll Life Sci, 88 East Wenhua Rd, Jinan 250014, Shandong, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2018年 / 54卷 / 04期
基金：
中国国家自然科学基金;
关键词：
endolichenic fungus; Myxotrichum sp; macrolide; phytotoxin; CLADOSPOLIDE-B; NONENOLIDE; MACROLIDE;
D O I：
10.1007/s10600-018-2435-7
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
One new macrolide myxotrilactone A (1), along with six known compounds (2-7), were isolated from the extract of solid-substrate cultures of the endolichenic fungus Myxotrichum sp. by various chromatography methods. The planar structure of compound 1 was determined by HR-ESI-MS and NMR data, and its relative and absolute configurations were established by NOESY experiment and comparison with the known compound 2. Selected isolates were evaluated for their allelopathic activities, and compounds. 1 and 2 significantly retarded shoot elongation of Arabidopsis thaliana.
引用
收藏
页码：638 / 641
页数：4
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