Efficient synthesis of 4-(2′-alkenyl)-2,5-dihydrofurans via PdCl2-catalyzed coupling-cyclization reaction of 2,3-allenols with allylic halides

被引：72
|
作者：
Ma, SM [1 ]
Gao, WZ [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 46期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/S0040-4039(00)01585-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4-(2'-Alkenyl)-2, 5-dihydrofurans can be efficiently synthesized via the PdCl2-catalyzed coupling-cyclization of allylic halides with 2,3-allenols in DMA at rt in moderate to good yields. The regioselectivity is different from that of the Pd(0)-catalyzed coupling-cyclization of organic halides with 2,3-allenols. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8933 / 8936
页数：4
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