Derivation of an HIV Risk Score for African Women Who Engage in Sex Work

被引：5
|
作者：
Willcox, Alexandra C. [1 ,2 ]
Richardson, Barbra A. [3 ,4 ,7 ]
Shafi, Juma [5 ,9 ]
Kabare, Emmanuel [5 ,9 ]
Kinuthia, John [10 ]
Jaoko, Walter [9 ]
Mandaliya, Kishorchandra [4 ]
Overbaugh, Julie [8 ]
McClelland, R. Scott [4 ,5 ,6 ,9 ]
机构：
[1] Univ Washington, Sch Med, Seattle, WA USA
[2] Univ Washington, Med Scientist Training Program, Seattle, WA 98195 USA
[3] Univ Washington, Dept Biostat, Seattle, WA 98195 USA
[4] Univ Washington, Dept Global Hlth, 325 9th Ave,Box 359909, Seattle, WA 98104 USA
[5] Univ Washington, Dept Med, Seattle, WA 98104 USA
[6] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
[7] Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Div, 1124 Columbia St, Seattle, WA 98104 USA
[8] Fred Hutchinson Canc Res Ctr, Human Biol Div, 1124 Columbia St, Seattle, WA 98104 USA
[9] Univ Nairobi, Dept Med Microbiol, Nairobi, Kenya
[10] Univ Nairobi, Kenyatta Natl Hosp, Nairobi, Kenya
来源：
AIDS AND BEHAVIOR | 2021年 / 25卷 / 10期
关键词：
HIV; Female sex workers; Africa; Kenya; Risk score; SEXUALLY-TRANSMITTED-DISEASES; HORMONAL CONTRACEPTION; VIRUS-INFECTION; CONDOM USE; FEMALE; ACQUISITION; MEN; TRANSMISSION; PREVENTION; PARTNERS;
D O I：
10.1007/s10461-021-03235-7
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
No tool exists to stratify HIV risk in contemporary African female sex worker (FSW) populations. Data from a cohort of HIV-negative FSWs in Mombasa, Kenya from 2010 to 2017 were used to conduct a survival analysis assessing predictors of HIV infection. Stepwise regression was used to construct a multivariable model that formed the basis for the score. Seventeen HIV infections occurred over 1247 person-years of follow-up contributed by 670 women. Using depot medroxyprogesterone acetate (DMPA), having a curable sexually transmitted infection (STI), and being married contributed points to the score. HIV incidence was 0.85/100 person-years in a lower-risk group and 3.10/100 person-years in a higher-risk group. In a cohort with overall HIV incidence < 1.50/100 person-years, this risk score identified a subgroup of FSWs with HIV incidence > 3.00/100 person-years, which is the threshold used by the World Health Organization for initiating pre-exposure prophylaxis (PrEP). If validated in an external population, this tool could be useful for targeted PrEP promotion among higher-risk FSWs.
引用
收藏
页码：3292 / 3302
页数：11
相关论文
共 50 条
  • [1] Derivation of an HIV Risk Score for African Women Who Engage in Sex Work
    Alexandra C. Willcox
    Barbra A. Richardson
    Juma Shafi
    Emmanuel Kabare
    John Kinuthia
    Walter Jaoko
    Kishorchandra Mandaliya
    Julie Overbaugh
    R. Scott McClelland
    [J]. AIDS and Behavior, 2021, 25 : 3292 - 3302
  • [2] Awakening as a change process among women at risk for HIV who engage in survival sex
    Mallory, C
    Stern, PN
    [J]. QUALITATIVE HEALTH RESEARCH, 2000, 10 (05) : 581 - 594
  • [3] HIV Prevention Among Women Who Use Substances And Report Sex Work: Risk Groups Identified Among South African Women
    Wendee M. Wechsberg
    Courtney Peasant
    Tracy Kline
    William A. Zule
    Jacqueline Ndirangu
    Felicia A. Browne
    Colby Gabel
    Charles van der Horst
    [J]. AIDS and Behavior, 2017, 21 : 155 - 166
  • [4] HIV Prevention Among Women Who Use Substances And Report Sex Work: Risk Groups Identified Among South African Women
    Wechsberg, Wendee M.
    Peasant, Courtney
    Kline, Tracy
    Zule, William A.
    Ndirangu, Jacqueline
    Browne, Felicia A.
    Gabel, Colby
    van der Horst, Charles
    [J]. AIDS AND BEHAVIOR, 2017, 21 (02) : S155 - S166
  • [5] A Validated Risk Score to Predict HIV Acquisition in African Women: Assessing Risk Score Performance among Women who Participated in the ASPIRE Trial
    Balkus, Jennifer
    Palnee-Phillips, Thesla
    Zhang, Jingyang
    Kiweewa, Flavia Matovu
    Nair, Gonasagrie
    Pather, Arendevi
    Siva, Samantha
    Govender, Vaneshree
    Naidoo, Logashvari
    Jeenarain, Nitesha
    Gafoor, Zakir
    Bekker, Linda-Gail
    Mbilizi, Yamikani
    Mgodi, Nyaradzo
    Brown, Elizabeth
    Baeten, Jared
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 2016, 32 : 49 - 49
  • [6] Personal and Financial Risk Typologies Among Women Who Engage in Sex Work in Mongolia: A Latent Class Analysis
    Reid Offringa
    Laura Cordisco Tsai
    Toivgoo Aira
    Marion Riedel
    Susan S. Witte
    [J]. Archives of Sexual Behavior, 2017, 46 : 1857 - 1866
  • [7] Personal and Financial Risk Typologies Among Women Who Engage in Sex Work in Mongolia: A Latent Class Analysis
    Offringa, Reid
    Tsai, Laura Cordisco
    Aira, Toivgoo
    Riedel, Marion
    Witte, Susan S.
    [J]. ARCHIVES OF SEXUAL BEHAVIOR, 2017, 46 (06) : 1857 - 1866
  • [8] Project Nova: A Combination HIV Prevention and Microfinance Intervention for Women Who Engage in Sex Work and Use Drugs in Kazakhstan
    Mergenova, Gaukhar
    El-Bassel, Nabila
    McCrimmon, Tara
    Terlikbayeva, Assel
    Primbetova, Sholpan
    Riedel, Marion
    Kuskulov, Azamat
    Velez-Grau, Carolina
    Witte, Susan S.
    [J]. AIDS AND BEHAVIOR, 2019, 23 (01) : 1 - 14
  • [9] Project Nova: A Combination HIV Prevention and Microfinance Intervention for Women Who Engage in Sex Work and Use Drugs in Kazakhstan
    Gaukhar Mergenova
    Nabila El-Bassel
    Tara McCrimmon
    Assel Terlikbayeva
    Sholpan Primbetova
    Marion Riedel
    Azamat Kuskulov
    Carolina Velez-Grau
    Susan S. Witte
    [J]. AIDS and Behavior, 2019, 23 : 1 - 14
  • [10] Engagement in sex work does not increase HIV risk for women who inject drugs in Ukraine
    Vasylyeva, Tetyana I.
    Friedman, Samuel R.
    Gensburg, Lenore
    Smyrnov, Pavlo
    [J]. JOURNAL OF PUBLIC HEALTH, 2017, 39 (03) : E103 - E110
12345