Missing genes in metabolic pathways: a comparative genomics approach

被引：232
|
作者：
Osterman, A [1 ]
Overbeek, R [1 ]
机构：
[1] Integrated Genomics Inc, Chicago, IL 60612 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2003年 / 7卷 / 02期
关键词：
D O I：
10.1016/S1367-5931(03)00027-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The new techniques of genome context analysis chromosomal gene clustering, protein fusions, occurrence profiles and shared regulatory sites - infer functional coupling between genes. In combination with metabolic reconstructions, these techniques can dramatically accelerate the pace of gene discovery.
引用
收藏
页码：238 / 251
页数：14
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