Utility of natriuretic peptide testing in the evaluation and management of acute decompensated heart failure

被引：4

作者：

Chiong, Jun R. ^{[1
]}

Jao, Geoffrey T. ^{[2
]}

Adams, Kirkwood F., Jr. ^{[3
,4
]}

机构：

[1] Loma Linda Univ, Med Ctr, Cardiomyopathy Program, Loma Linda, CA 92354 USA

[2] Wake Forest Univ, Gen Internal Med Sect, Baptist Med Ctr, Winston Salem, NC 27157 USA

[3] Univ N Carolina, Dept Med, Chapel Hill, NC 27599 USA

[4] Univ N Carolina, Dept Radiol, Chapel Hill, NC 27599 USA

来源：

HEART FAILURE REVIEWS | 2010年 / 15卷 / 04期

关键词：

Natriuretic peptides; Acute heart failure; Prognosis; EMERGENCY-DEPARTMENT PRIDE; THROMBOEMBOLIC PULMONARY-HYPERTENSION; VENTRICULAR SYSTOLIC DYSFUNCTION; CHRONIC KIDNEY-DISEASE; BODY-MASS INDEX; ACUTE DYSPNEA; NT-PROBNP; SEPTIC SHOCK; CARDIOVASCULAR-DISEASE; HEMODIALYSIS-PATIENTS;

D O I：

10.1007/s10741-009-9141-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The B-type natriuretic peptide (BNP) and the amino-terminal fragment of proBNP (NT-proBNP) are increased in heart failure in proportion to severity of symptoms, degree of left ventricular dysfunction, and elevation of cardiac filling pressures. These natriuretic peptides (NPs) are increasingly used for diagnostic and prognostic purposes in acute heart failure. While NP levels on admission provide independent prognostic information, serial determinations during hospitalization and at discharge better reflect adequacy of treatment and prognosis. The addition of BNP and NT-proBNP to usual clinical decision making enhances detection of high-risk patients who need aggressive follow-up and adjustment of treatment.

引用

页码：275 / 291

页数：17

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