In Silico Molecular Docking-Based Screening Reveals Phytomolecules Against SARS-COV-2 Main Protease

In past two decades, the globe has faced many infectious disease outbreaks. 2019 Novel Corona-virus (2019-nCoV) or the severe acute respiratory syndrome Corona-virus 2 (SARS-CoV-2) emerged as a global risk and put the entire globe into unrest. Unavailability of specific drug against the virus is more imperative. This demanding situation requires development of bio molecules for competent treatment against the SARS-CoV-2. The crystal structure of SARS-CoV-2 main protease (Mpro) may be used for fast in silico docking and novel pharmacophores can be discovered. This may result into identification of active bio-molecules largely phytochemicals. In silico Molecular Docking revealed that the phytochemical, Gallic acid effectively binds to the active pocket of the SARS-CoV-2 main protease.