Molecular docking analysis of antimicrobial peptides with the CXCL1 protein target for colorectal cancer

被引:1
|
作者
Kumar, Praveen Kumar [1 ]
Piramanayagam, Shanmughavel [1 ]
机构
[1] Bharathiar Univ, Dept Bioinformat, Computat Biol Lab, Coimbatore 641046, Tamil Nadu, India
关键词
Antimicrobial peptides; colorectal cancer; Peptide docking; Schrodinger;
D O I
10.6026/97320630017369
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Antimicrobial peptides (AMPs) play a prominent role in drug discovery due to the rapid increase in drug resistant infections. Hence, we report the molecular docking analysis of antimicrobial peptides MREEKKERKRD and MVQGAKRGGRLHRV with the target protein CXCL1 in the context of colorectal cancer for further consideration in drug discovery.
引用
收藏
页码:369 / 376
页数:8
相关论文
共 50 条
  • [41] Molecular investigation of antimicrobial peptides against Helicobacter pylori proteins using a peptide-protein docking approach
    Hanafiah, Alfizah
    Abd Aziz, Siti Nur Arifah
    Nesran, Zarith Nameyrra Md
    Wezen, Xavier Chee
    Ahmad, Mohd Fadzli
    HELIYON, 2024, 10 (06)
  • [42] Urine CXCL1 as a biomarker for tumor detection and outcome prediction in bladder cancer
    Nakashima, Masakazu
    Matsui, Yoshiyuki
    Kobayashi, Takashi
    Saito, Ryoichi
    Hatahira, Satoko
    Kawakami, Kazumi
    Nakamura, Eijiro
    Nishiyama, Hiroyuki
    Ogawa, Osamu
    CANCER BIOMARKERS, 2015, 15 (04) : 357 - 364
  • [43] Analysis of target functions for protein-protein docking
    Gatchell, DW
    Camacho, CJ
    Vajda, S
    BIOPHYSICAL JOURNAL, 2001, 80 (01) : 497A - 497A
  • [44] Marrow adipocyte-derived CXCL1 and CXCL2 contribute to osteolysis in metastatic prostate cancer
    Hardaway, Aimalie L.
    Herroon, Mackenzie K.
    Rajagurubandara, Erandi
    Podgorski, Izabela
    CLINICAL & EXPERIMENTAL METASTASIS, 2015, 32 (04) : 353 - 368
  • [45] Th17 cells regulate the production of CXCL1 in breast cancer
    Ma, Kai
    Yang, Lihua
    Shen, Ruowu
    Kong, Bin
    Chen, Wenting
    Liang, Jie
    Tang, Guoqing
    Zhang, Bei
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 56 : 320 - 329
  • [46] Progesterone and calcitriol attenuate inflammatory cytokines CXCL1 and CXCL2 in ovarian and endometrial cancer cells
    Kavandi, Leyla
    Collier, Michael A.
    Huyen Nguyen
    Syed, Viqar
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2012, 113 (10) : 3143 - 3152
  • [47] CXCL1 activates TRPV1 via Gi/o protein and actin filaments
    Deftu, Alexandru Florian
    Filippi, Alexandru
    Gheorghe, Roxana Olimpia
    Ristoiu, Violeta
    LIFE SCIENCES, 2018, 193 : 282 - 291
  • [48] Survivin as a Target for Anti-cancer Phytochemicals According to the Molecular Docking Analysis
    Kobra Foroughi
    Sarvin Jahanbani
    Simin Nazarnezhad
    Hossein Khastar
    Moslem Jafarisani
    Mersedeh Tashakori
    Seyedeh Sareh Kazemi
    International Journal of Peptide Research and Therapeutics, 2020, 26 : 1115 - 1126
  • [49] Survivin as a Target for Anti-cancer Phytochemicals According to the Molecular Docking Analysis
    Foroughi, Kobra
    Jahanbani, Sarvin
    Nazarnezhad, Simin
    Khastar, Hossein
    Jafarisani, Moslem
    Tashakori, Mersedeh
    Kazemi, Seyedeh Sareh
    INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2020, 26 (02) : 1115 - 1126
  • [50] Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer
    Friedrich, Teresa
    Soehn, Michaela
    Gutting, Tobias
    Janssen, Klaus-Peter
    Behrens, Hans-Michael
    Roecken, Christoph
    Ebert, Matthias P. A.
    Burgermeister, Elke
    EBIOMEDICINE, 2016, 8 : 159 - 172