Bortezomib Is Effective in Treating T-ALL, Inducting G2/M Cell Cycle Arrest and WEE1 Downregulation

被引：1
|
作者：
Sin Chun-fung [1 ]
Wan, Timothy Ming-hun [1 ]
Mohan, Aarmann Anil Mohinani [1 ]
Qiu, Yinxia [1 ]
Jiao, Anan [1 ]
机构：
[1] Univ Hong Kong, Dept Pathol, Hong Kong, Peoples R China
来源：
BLOOD | 2021年 / 138卷
关键词：
D O I：
10.1182/blood-2021-149455
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
4360
引用
收藏
页数：5
相关论文
共 50 条
  • [1] Autophagy modulates the stability of Wee1 and cell cycle G2/M transition
    Han, Biwei
    Chen, Yajing
    Song, Chen
    Chen, Yali
    Chen, Yong
    Ferguson, Daniel
    Yang, Yunzhi
    He, Anyuan
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 677 : 63 - 69
  • [2] C/EBPβ Is a Transcriptional Regulator of Wee1 at the G2/M Phase of the Cell Cycle
    Lee, Ji Hae
    Sung, Jee Young
    Choi, Eun Kyung
    Yoon, Hyun-Kyoung
    Kang, Bo Ram
    Hong, Eun Kyung
    Park, Byung-Kiu
    Kim, Yong-Nyun
    Rho, Seung Bae
    Yoon, Kyungsil
    CELLS, 2019, 8 (02)
  • [3] Spatiotemporal regulations of Wee1 at the G2/M transition
    Masuda, Hirohisa
    Fong, Chii Shyang
    Ohtsuki, Chizuru
    Haraguchi, Tokuko
    Hiraoka, Yasushi
    MOLECULAR BIOLOGY OF THE CELL, 2011, 22 (05) : 555 - 569
  • [4] DRG2 binds to Wee1 for regulating cell cycle progression during G2/M phase
    Jang, S.
    Park, N.
    Kim, S.
    Park, J.
    Han, I.
    MOLECULAR BIOLOGY OF THE CELL, 2014, 25
  • [5] Bortezomib Is Effective in the Treatment of T Lymphoblastic Leukaemia by Inducing DNA Damage, WEE1 Downregulation, and Mitotic Catastrophe
    Din, Rahman Ud
    Jiao, Anan
    Qiu, Yinxia
    Mohan, Aarmann Anil Mohinani
    Yuen, Kei-Ching
    Wong, Hoi-Tung
    Wan, Timothy Ming-Hun
    Wong, Phoebe On-Yi
    Sin, Chun-Fung
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (19)
  • [6] WEE1 kinase inhibition reverses G2/M cell cycle checkpoint activation to sensitize cancer cells to immunotherapy
    Sun, Lillian
    Moore, Ellen
    Berman, Rose
    Clavijo, Paul E.
    Saleh, Anthony
    Chen, Zhong
    Van Waes, Carter
    Davies, John
    Friedman, Jay
    Allen, Clint T.
    ONCOIMMUNOLOGY, 2018, 7 (10):
  • [7] CCAAT/Enhancer-binding protein beta is a critical regulator of Wee1 in G2/M cell cycle progression
    Choi, E.
    Yoon, Kyungsil
    Yoon, K.
    FEBS JOURNAL, 2014, 281 : 66 - 66
  • [8] INCREASING TUMOR TREATING FIELDS (TTFIELDS) EFFICACY BY TARGETING THE G2 CELL CYCLE CHECKPOINT WITH WEE1 OR CHK1 INHIBITORS IN GLIOBLASTOMA CELL LINES
    Slangen, Paul L. G.
    de Gooijer, Mark C.
    van Geldorp, Mariska
    van Tellingen, Olaf
    Borst, Gerben R.
    NEURO-ONCOLOGY, 2020, 22 : 93 - 93
  • [9] Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases
    Schmidt, Matthias
    Rohe, Alexander
    Platzer, Charlott
    Najjar, Abdulkarim
    Erdmann, Frank
    Sippl, Wolfgang
    MOLECULES, 2017, 22 (12):
  • [10] G2/M cell cycle arrest in the life cycle of viruses
    Davy, Clare
    Doorbar, John
    VIROLOGY, 2007, 368 (02) : 219 - 226
12345