Efficient and mild method for preparation of allylic amines from aziridine-2-alcohols using PPh3/I2/imidazole

被引：23
|
作者：
Chavan, Subhash P. [1 ]
Khairnar, Lalit B. [1 ]
Chavan, Prakash N. [1 ]
机构：
[1] CSIR, NCL, Div Organ Chem, Pune 411008, Maharashtra, India
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 43期
关键词：
PPh3/iodine/imidazole; Reductive elimination; Chiral aziridine-2-alcohols; Chiral allylic amine; BOND-FORMING HYDROGENATION; BIFUNCTIONAL ORGANOCATALYSTS; REDUCTIVE ALKYLATION; IMINE VINYLATION; AMINATION; CONVERSION; ALCOHOLS; 2-(BROMOMETHYL)AZIRIDINES; MONOALLYLATION; ORGANOLITHIUM;
D O I：
10.1016/j.tetlet.2014.08.078
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Allylic amines are synthesized in good to excellent yields by treatment of aziridine-2-alcohols with PPh3/I-2/imidazole in THF as solvent under mild conditions. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5905 / 5907
页数：3
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