Three megastigmane glycosides from the leaves of Pterospermum semisagittatum

被引：34
|
作者：
Khan, SH
Mosihuzzaman, M
Nahar, N [1 ]
Rashid, MA
Rokeya, B
Ali, L
Khan, AKA
机构：
[1] Univ Dhaka, Dept Chem, Dhaka 1000, Bangladesh
[2] Univ Dhaka, Dept Pharm, Dhaka 1000, Bangladesh
[3] Bangladesh Inst Res & Rehabil Diabet Endocrine &, Res & Acad Div, Dhaka 1000, Bangladesh
来源：
PHARMACEUTICAL BIOLOGY | 2003年 / 41卷 / 07期
关键词：
Pterospermum semisagittatum; megastigmane; antihyperglycemic; ELISA; insulin release;
D O I：
10.1080/13880200308951345
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Pterospermum semisagittatum leaves yielded three megastigmane glycosides (Z)-4-[3'-(beta-D-glucopyranosyloxy) butylidene]-3,5,5-trimethyl-2-cyclohexen-1-one (1), (E)-4[3'-(beta-D-glucopyranosyloxy)butylidene]-3,5,5-trimethyl- 2-cyclohexen-1-one (2) and (E)-4-hydroxy-4-[3'-((3-D-glucopyranosyloxy)butylidene]-3,5,5-trimethyl-2- cyclohexen-l-one (3). Their structures were established by detailed spectroscopic studies. Compound 3 showed a significant insulin releasing effect on rat pancreatic islets.
引用
收藏
页码：512 / 515
页数：4
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