The main function of gas turbine blades is to rotate the shaft which is connected to the generating motor. In power plant, a gas turbine blade is subjected to very high vibrations, pressure and temperature because of which material used for manufacturing should be able to withstand these extreme working conditions. In this study, the maximum stress and deformation generated by the centrifugal force acting on a gas turbine blade have been determined. In addition, the natural frequencies of vibrations are determined, which are due to rotation at a very high speed under high thermal conditions. In this paper, four different materials are selected for the gas turbine blade including Titanium alloy, Nimonic 80 A, INCONEL alloy 617, and Rhenium. Subsequently, four materials are analysed to select the best-suited material for manufacturing of the gas turbine blade. Three-dimensional CAD model of a gas turbine blade is modelled using SolidWorks 2018 and the finite element analysis (FEA) based static structural, thermal and modal analyses are carried out using ANSYS 2019. ? 2021 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the International Conference on Materials, Processing & Characterization.