Modulation of the Gut Microbiota by Nutrients with Prebiotic and Probiotic Properties

被引：70
|
作者：
Druart, Celine [1 ]
Alligier, Maud [1 ]
Salazar, Nuria [1 ]
Neyrinck, Audrey M. [1 ]
Delzenne, Nathalie M. [1 ]
机构：
[1] Catholic Univ Louvain, Louvain Drug Res Inst, Metab & Nutr Res Grp, B-1200 Brussels, Belgium
来源：
ADVANCES IN NUTRITION | 2014年 / 5卷 / 05期
关键词：
HIGH-FAT-DIET; LACTOBACILLUS-GASSERI SBT2055; GLUCAGON-LIKE PEPTIDE-1; CONJUGATED LINOLEIC-ACID; INDUCED OBESE MICE; OLIGOFRUCTOSE PROMOTES SATIETY; RANDOMIZED CONTROLLED-TRIAL; INULIN-TYPE FRUCTANS; METABOLIC SYNDROME; INSULIN SENSITIVITY;
D O I：
10.3945/an.114.005835
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Experimental data in animals, but also observational studies in humans, suggest that the composition of the gut microbiota differs in obese vs. lean individuals, in patients with vs. without diabetes, or in patients presenting other diseases associated with obesity or nutritional disbalance, such as non-alcoholic fatty liver disease (NAFLD) or cardiovascular diseases. In this review, we describe how changes in the composition and/or activity of the gut microbiota by administration of nutrients with probiotic or prebiotic properties can modulate host gene expression and metabolism and thereby positively influence host adipose tissue development and related metabolic disorders.
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页码：624S / 633S
页数：10
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