Microwave-assisted cycloaddition reactions

被引:156
|
作者
Appukkuttan, Prasad [1 ]
Mehta, Vaibhav P. [1 ]
Van der Eycken, Erik V. [1 ]
机构
[1] Katholieke Univ Leuven, LOMAC, Dept Chem, B-3001 Heverlee, Belgium
关键词
CLICK CHEMISTRY; 1,3-DIPOLAR CYCLOADDITIONS; AZIDES; ANALOG; CORE; ACID;
D O I
10.1039/b815717k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cycloaddition reactions belong to one of the most well-investigated and widely used reactions in synthetic organic chemistry for the construction of (hetero) cyclic compounds in a single-step operation. In this tutorial review, a select number of examples of some [3 + 2] cycloadditions, i.e. for 1,2,3-triazole formation, as well as of some [4 + 2] and [2 + 2] cycloadditions are reviewed, where it has been proven that the application of microwave irradiation has a profound influence on the outcome of the reaction.
引用
收藏
页码:1467 / 1477
页数:11
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