Nitroxide radical-modified CuS nanoparticles for CT/MRI imaging-guided NIR-II laser responsive photothermal cancer therapy

被引：4

作者：

Xia, Chengwan ^{[1
]}

Xie, Diya ^{[1
]}

Xiong, Lang ^{[1
]}

Zhang, Qian ^{[1
]}

Wang, Yang ^{[1
]}

Wang, Zezheng ^{[1
]}

Wang, Yuxin ^{[1
]}

Li, Bin ^{[1
]}

Zhang, Chao ^{[1
,2
]}

机构：

[1] Nanjing Univ, Nanjing Stomatol Hosp, Med Sch, Nanjing 210093, Jiangsu, Peoples R China

[2] Nanjing Univ, Collaborat Innovat Ctr Chem Life Sci, Coll Engn & Appl Sci, Nanjing 210093, Jiangsu, Peoples R China

来源：

RSC ADVANCES | 2018年 / 8卷 / 48期

关键词：

MICROENVIRONMENTAL REGULATION; COMPUTED-TOMOGRAPHY; GOLD NANOPARTICLES; GENE TRANSFECTION; CONTRAST AGENTS; DRUG-DELIVERY; CHEMOTHERAPY; GRAPHENE; OXIDE; STERILIZATION;

D O I：

10.1039/c8ra04501a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we reported nitroxide radical-modified CuS nanoparticles (CuS-NO center dot NPs), and they exhibited a typical absorption peak at 1182 nm. Due to such a long wavelength absorbance, CuS-NO center dot NPs exhibited excellent therapeutic outcome and low damage to normal tissues. Besides, we simultaneously achieved CuS-NO center dot NPs for MRI and CT dual-modal imaging, which successfully provided a new strategy for imaging-guided tumor treatment, thus increasing potential clinical applications for cancer treatment.

引用

页码：27382 / 27389

页数：8

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