Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension

被引：4

作者：

Zhang, Shenglin ^{[1
]}

Gao, Xin ^{[2
]}

Wang, Dongxia ^{[2
]}

Jiang, Yinong ^{[2
]}

Liu, Yan ^{[2
]}

机构：

[1] Dalian Med Univ, Dept Gen Surg, Affiliated Hosp 1, Zhongshan Rd 222, Dalian, Liaoning, Peoples R China

[2] Dalian Med Univ, Dept Cardiol, Affiliated Hosp 1, Lianhe Rd 193, Dalian, Liaoning, Peoples R China

来源：

INTERNATIONAL JOURNAL CARDIOLOGY HYPERTENSION | 2019年 / 2卷

基金：

中国国家自然科学基金;

关键词：

PAC; Atrial function; Hypertension; HEART; APOPTOSIS;

D O I：

10.1016/j.ijchy.2019.100015

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LA(S-E) and LA(SR-E)) were lower in group II compared with group I (P < 0.05). Multivariate regression analysis showed that LA(S-E) was independently related to PAC (beta = -0.581, P < 0.001). In conclusion, PAC is associated with LA conduit function in hypertension.

引用

页数：4

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