MMP-12 inhibitors

被引：0
|
作者：
不详
机构：
来源：
EXPERT OPINION ON THERAPEUTIC PATENTS | 2004年 / 14卷 / 11期
关键词：
asthma; chronic obstructive pulmonary disease (COPD); elastase; emphysema; matrix metalloproteinase (MMP); MMP-9; MMP-12;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Novel N-arylalkyl 5-hydantoin acetamide derivatives are claimed. These compounds are shown to be potent matrix metalloproteinase-12 (MMP-12) inhibitors, and their use for the treatment of asthma and chronic obstructive pulmonary disease (COPD) is claimed. This application is one of a large series of applications claiming closely-related compounds as inhibitors of certain MMPs.
引用
收藏
页码：1637 / 1640
页数：4
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