Serpins are getting hotter

被引:0
|
作者
Salvesen, GS [1 ]
Scott, FL [1 ]
机构
[1] Burnham Inst, Program Apoptosis & Cell Death Res, La Jolla, CA 92037 USA
关键词
D O I
10.1016/S0969-2126(03)00058-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Protease inhibitors of the serpin family require thermodynamic instability for their mechanism of inhibition, and a recent paper from Irving and colleagues demonstrates the structural basis for how a serpin from a bacterial thermophile deals with life at elevated temperature.
引用
收藏
页码:364 / 365
页数:2
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