A Novel Cause of Familial Hypercholesterolemia: PCSK9 Gene Duplication

被引：3
|
作者：
Paquette, Martine [1 ]
Baass, Alexis [1 ,2 ,3 ]
机构：
[1] Montreal Clin Res Inst, Lipids Nutr & Cardiovasc Prevent Clin, 110 Ave Pins Ouest, Montreal, PQ H2W 1R7, Canada
[2] McGill Univ, Div Expt Med, Dept Med, Montreal, PQ, Canada
[3] McGill Univ, Div Med Biochem, Dept Med, Montreal, PQ, Canada
来源：
CANADIAN JOURNAL OF CARDIOLOGY | 2018年 / 34卷 / 10期
关键词：
AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA; DENSITY-LIPOPROTEIN RECEPTOR; MUTATIONS;
D O I：
10.1016/j.cjca.2018.08.027
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1259 / 1260
页数：2
相关论文
共 50 条
  • [1] WHOLE-GENE DUPLICATION OF PCSK9 AS A NOVEL GENETIC MECHANISM FOR FAMILIAL HYPERCHOLESTEROLEMIA
    Iacocca, Michael A.
    Wang, Jian
    Lagace, Thomas
    McIntyre, Adam D.
    Lau, Paulina
    Cao, Henian
    McPherson, Ruth
    Hegele, Robert A.
    ATHEROSCLEROSIS SUPPLEMENTS, 2018, 32 : 9 - 10
  • [2] Whole-Gene Duplication of PCSK9 as a Novel Genetic Mechanism for Severe Familial Hypercholesterolemia
    Iacocca, Michael A.
    Wang, Jian
    Sarkar, Samantha
    Dron, Jacqueline S.
    Lagace, Thomas
    McIntyre, Adam D.
    Lau, Paulina
    Robinson, John F.
    Yang, Ping
    Knoll, Joan H.
    Cao, Henian
    McPherson, Ruth
    Hegele, Robert A.
    CANADIAN JOURNAL OF CARDIOLOGY, 2018, 34 (10) : 1316 - 1324
  • [3] PCSK9 IN FAMILIAL HYPERCHOLESTEROLEMIA (FH)
    Lambert, G.
    Rye, K. -A.
    Burnett, J.
    Barter, P.
    Marais, D.
    ATHEROSCLEROSIS SUPPLEMENTS, 2011, 12 (01) : 31 - 31
  • [4] PCSK9 Inhibitors for Familial Hypercholesterolemia
    Lenahan, Christy M.
    Harringtoon, Deedra
    JNP-JOURNAL FOR NURSE PRACTITIONERS, 2016, 12 (08): : 577 - 578
  • [5] PCSK9 gene analysis in Portuguese patients with familial hypercholesterolemia
    Alves, A. C.
    Rato, Q.
    Furtado, A.
    Bourbon, M.
    ATHEROSCLEROSIS SUPPLEMENTS, 2007, 8 (01) : 214 - 215
  • [6] SCREENING OF PCSK9 GENE IN INDIAN FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS
    Reddy, L. L.
    Ponde, C. K.
    Rajani, R. M.
    Pillai, S.
    Dalal, R. J.
    Vanjani, C. V.
    Dalal, J.
    Ashavaid, T. F.
    ATHEROSCLEROSIS, 2019, 287 : E212 - E212
  • [7] PCSK9 inhibition in the management of familial hypercholesterolemia
    Ogura, Masatsune
    JOURNAL OF CARDIOLOGY, 2018, 71 (1-2) : 1 - 7
  • [8] PCSK9 INHIBITOR UTILIZATION IN FAMILIAL HYPERCHOLESTEROLEMIA
    Jackson, Candace
    Deng, Yihong
    Yao, Xiaoxi
    Van Houten, Holly
    Shah, Nilay
    Kopecky, Stephen
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (11) : 1873 - 1873
  • [9] PCSK9 inhibitors in familial hypercholesterolemia: What is the evidence?
    Paquette, Martine
    Hegele, Robert A.
    Baass, Alexis
    JOURNAL OF CLINICAL LIPIDOLOGY, 2018, 12 (05) : 1106 - 1108
  • [10] PCSK9 in South African Variants of Familial Hypercholesterolemia
    Getz, Godfrey S.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 63 (22) : 2374 - 2375
12345