Elastic Fully Three-dimensional Microstructure Scaffolds for Cell Force Measurements

被引：148

作者：

Klein, Franziska ^{[1
,2
]}

Striebel, Thomas ^{[2
,3
]}

Fischer, Joachim ^{[2
,3
]}

Jiang, Zhongxiang ^{[1
,2
]}

Franz, Clemens M. ^{[2
]}

von Freymann, Georg ^{[2
,3
,4
]}

Wegener, Martin ^{[2
,3
,4
]}

Bastmeyer, Martin ^{[1
,2
]}

机构：

[1] Univ Karlsruhe TH, Inst Zool, D-76131 Karlsruhe, Germany

[2] Univ Karlsruhe TH, CFN, DFG, D-76131 Karlsruhe, Germany

[3] Univ Karlsruhe TH, Inst Angew Phys, D-76131 Karlsruhe, Germany

[4] Forschungszentrum Karlsruhe Helmholtz Gemeinschaf, Inst Nanotechnol, D-76021 Karlsruhe, Germany

来源：

ADVANCED MATERIALS | 2010年 / 22卷 / 08期

关键词：

D O I：

10.1002/adma.200902515

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Elastic 3D scaffolds (see figure) are fabricated into a biocompatible photoresist using direct laser writing. These scaffolds can be rhythmically deformed by single beating cardiomyocytes and calibration with atomic force microscopy indicates that cellular forces down to 10-20 nN are detectable with the setup.

引用

页码：868 / +

页数：5

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