Efficient synthesis of chiral homodimeric 4-(N,N-dimethylamino)pyridine carbamate derivatives

The synthesis of a novel family of optically active 4-(N,N-dimethylamino)pyridine carbamate derivatives has been achieved with excellent isolated yields using different linear diamines as starting materials to produce dimeric compounds of variable length. Optically active homodimeric 4-(N,N-dimethylamino)pyridine carbamate derivatives obtained through this chemoenzymatic route present interesting structural properties as possible ligands or nucleophilic catalysts in asymmetric catalysis.