Huntington's disease: Managing neuropsychiatric symptoms in Huntington's disease

被引:11
|
作者
Loi, Samantha M. [1 ,2 ,3 ]
Walterfang, Mark [1 ,3 ,4 ]
Velakoulis, Dennis [1 ,3 ,4 ]
Looi, Jeffrey C. L. [1 ,4 ,5 ]
机构
[1] Royal Melbourne Hosp, Neuropsychiat Unit, John Cade Level 2,Grattan St, Parkville, Vic 3050, Australia
[2] Univ Melbourne, Dept Psychiat, Parkville, Vic, Australia
[3] NorthWestern Mental Hlth, Parkville, Vic, Australia
[4] Univ Melbourne, Melbourne Neuropsychiat Ctr, Parkville, Vic, Australia
[5] Australian Natl Univ, Med Sch, Canberra Hosp, Acad Unit Psychiat & Addict Med, Canberra, ACT, Australia
关键词
huntington's disease; neuropsychiatric symptoms; psychiatry; STIMULATION;
D O I
10.1177/1039856218766120
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objectives: This clinical update review focuses on the management of the neuropsychiatric manifestations of Huntington's disease (HD). The review highlights current issues regarding pharmacological and non-pharmacological treatment, putative therapeutics and recent relevant research findings in this area. Conclusions: Neuropsychiatric symptoms may precede the classic motor clinical symptoms of HD (prodromal HD) by decades and cause significant functional impairment. Early recognition and comprehensive non-pharmacological, usually in combination with pharmacological, treatment is essential.
引用
收藏
页码:376 / 380
页数:5
相关论文
共 50 条
  • [1] Neuropsychiatric symptoms of huntington's disease
    Santos, N.
    Alho, A.
    Santos, C.
    Gasparinho, R.
    Ferreira, L.
    Martins, M.
    Fernandes, N.
    Seco, E.
    [J]. EUROPEAN PSYCHIATRY, 2020, 63 : S432 - S433
  • [2] Managing Huntington's disease - the neuropsychiatric approach
    Coelho, I.
    Reis, J.
    Lazaro, M.
    Goncalves, F.
    Passao, V.
    Cunha, I.
    [J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2019, 29 : S543 - S544
  • [3] Huntington's disease: Neuropsychiatric manifestations of Huntington's disease
    Goh, Anita M. Y.
    Wibawa, Pierre
    Loi, Samantha M.
    Walterfang, Mark
    Velakoulis, Dennis
    Looi, Jeffrey C. L.
    [J]. AUSTRALASIAN PSYCHIATRY, 2018, 26 (04) : 366 - 375
  • [4] Neuropsychiatric Symptoms and Premanifest Huntington's Disease
    Saenz-Farret, Michel
    Zuniga-Ramirez, Carlos
    Ramirez-Gomez, Carolina Candelaria
    Montilla-Uzcategui, Veronica
    Micheli, Federico
    [J]. MOVEMENT DISORDERS, 2017, 32 (03) : 481 - 481
  • [5] Neuropsychiatric Symptoms and Functional Capacity in Huntington's Disease
    Sellers, J.
    Ridner, S.
    Claassen, D.
    [J]. NEUROTHERAPEUTICS, 2018, 15 (04) : 1196 - 1197
  • [6] Longitudinal Evaluation of Neuropsychiatric Symptoms in Huntington's Disease
    Thompson, Jennifer C.
    Harris, Jenny
    Sollom, Andrea C.
    Stopford, Cheryl L.
    Howard, Elizabeth
    Snowden, Julie S.
    Craufurd, David
    [J]. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 2012, 24 (01) : 53 - 60
  • [7] ANATOMICAL SUBSTRATES FOR NEUROPSYCHIATRIC SYMPTOMS IN PATIENTS WITH HUNTINGTON'S DISEASE
    Kamble, N.
    Saini, J.
    Netravathi, M.
    Jain, S.
    Pal, P. K.
    [J]. PARKINSONISM & RELATED DISORDERS, 2020, 79 : E107 - E107
  • [8] The influence of neuropsychiatric symptoms on functional disability in Huntington's disease
    Banaszkiewicz, K.
    Bielanska, M.
    Klimiec, E.
    Nieweglowska, D.
    Banach, M.
    Rudzinska, M.
    Szczudlik, A.
    [J]. MOVEMENT DISORDERS, 2011, 26 : S59 - S59
  • [9] Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY)
    van Duijn, Erik
    Craufurd, David
    Hubers, Anna A. M.
    Giltay, Erik J.
    Bonelli, Raphael
    Rickards, Hugh
    Anderson, Karen E.
    van Walsem, Marleen R.
    van der Mast, Rose C.
    Orth, Michael
    Landwehrmeyer, G. Bernhard
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2014, 85 (12): : 1411 - 1418
  • [10] The neuropsychiatric manifestations of Huntington's disease
    Naarding, P
    Janzing, JGE
    [J]. CURRENT OPINION IN PSYCHIATRY, 2003, 16 (03) : 337 - 340