MR spectroscopy of cervical spinal cord in patients with multiple sclerosis

被引:54
|
作者
Kendi, ATK
Tan, FU
Kendi, M
Huvaj, S
Tellioglu, S
机构
[1] Kirikkale Univ, Sch Med, Dept Neurol, Kirikkale, Turkey
[2] Kirikkale Univ, Sch Med, Dept Radiol, Kirikkale, Turkey
关键词
multiple sclerosis; magnetic resonance spectroscopy; spinal cord;
D O I
10.1007/s00234-004-1231-1
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
MR spectroscopy (MRS) of the brain in patients with multiple sclerosis has been well studied. However, in vivo MRS of the spinal cord in patients with MR spectroscopy has not been reported to our knowledge. We performed MRS of normal-appearing cervical spinal cords in multiple sclerosis patients and in healthy controls. N-acetyl aspartate was shown to be reduced within the cervical spinal cord of multiple sclerosis patients when compared with healthy controls. This finding supports axonal loss and damage within even normal-appearing spinal cords of multiple sclerosis patients.
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页码:764 / 769
页数:6
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