Efficient synthesis of multiply substituted butenolides from keto acids and terminal alkynes promoted by combined acids

被引：4
|
作者：
Mao, Wenbin [1 ]
Zhu, Chen [1 ,2 ]
机构：
[1] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, 199 Ren Ai Rd, Suzhou 215123, Jiangsu, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, 345 Lingling Rd, Shanghai 200032, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2017年 / 4卷 / 06期
基金：
中国国家自然科学基金;
关键词：
ONE-POT SYNTHESIS; TRIPTERYGIUM-WILFORDII; METHYL ISOANTICOPALATE; MARINE SPONGE; INHIBITORS; DYSIDIOLIDE; CONSTITUENTS; ANTAGONISTS; TERPENOIDS; ANNULATION;
D O I：
10.1039/c6qo00820h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A general, efficient, and operationally simple approach to highly substituted butenolides through the annulation of keto acids and terminal alkynes is described. This reaction is promoted by the combination of Lewis and Bronsted acids, furnishing a variety of butenolides in synthetically useful yields.
引用
收藏
页码：1029 / 1033
页数：5
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