First Efficient Synthesis of Fluorinated Glycidic Esters from Ketones

被引：26
|
作者：
Lemonnier, Gerald
Zoute, Ludivine
Quirion, Jean-Charles
Jubault, Philippe [1 ]
机构：
[1] INSA, F-76821 Mont St Aignan, France
来源：
ORGANIC LETTERS | 2010年 / 12卷 / 04期
关键词：
CARBONYL; ALDEHYDES; CHEMISTRY; REAGENT;
D O I：
10.1021/ol902903v
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of various ketones with ethyl dibromofluoroacetate in the presence of diethylzinc and dimethylaminoethanol or triphenylphosphine provides rapid access to corresponding fluorinated glycidic esters. Simplified workup allowed first characterization of these compounds.
引用
收藏
页码：844 / 846
页数：3
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