PML-RARα: changing myeloid networks

被引:1
|
作者
Kogan, Scott C. [1 ]
机构
[1] Univ Calif San Francisco, San Francisco, CA 94143 USA
关键词
LEUKEMIA; PROGENITOR; TARGET;
D O I
10.1182/blood.2020008849
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this issue of Blood, Tan et al identify novel cooperative effects of the promyelocytic leukemia/retinoic acid receptor-alpha (PML/RAR alpha) chimeric fusion and the growth factor independent-1 (GFI1) transcriptional repressor that underlie aberrant cell fate decisions characteristic of acute promyelocytic leukemia (APL).(1)
引用
收藏
页码:1439 / 1440
页数:3
相关论文
共 50 条
  • [1] Regulation of NF-κB by PML and PML-RARα
    Ahmed, Abrar
    Wan, Xiaochun
    Mitxitorena, Izaskun
    Lindsay, Andrew J.
    Pandolfi, Pier Paolo
    McCaffrey, Mary W.
    Keeshan, Karen
    Chen, Youhai H.
    Carmody, Ruaidhri J.
    SCIENTIFIC REPORTS, 2017, 7
  • [2] PML-RARα/pIRES和PML-RARα/pSecTag重组载体的构建和鉴定
    汤冀
    李扬秋
    周羽竝
    杨力建
    陈少华
    胡刚
    罗更新
    现代临床医学生物工程学杂志, 2006, (03) : 280 - 283
  • [3] Constitution and identification of PML-RARα/PIRES and PML-RARα-GM-CSF/PIRES recombinant plasmids
    Li, Y.
    Hu, G.
    Tang, J.
    Zhou, Y.
    Chen, S.
    Yang, L.
    Przybylski, G.
    Schmidt, C. A.
    EXPERIMENTAL HEMATOLOGY, 2007, 35 (09) : 89 - 89
  • [4] Regulation of NF-κB by PML and PML-RARα
    Abrar Ahmed
    Xiaochun Wan
    Izaskun Mitxitorena
    Andrew J. Lindsay
    Pier Paolo Pandolfi
    Mary W. McCaffrey
    Karen Keeshan
    Youhai H. Chen
    Ruaidhrí J. Carmody
    Scientific Reports, 7
  • [5] The PML domain of PML-RARα blocks senescence to promote leukemia
    Korf, Katharina
    Wodrich, Harald
    Haschke, Alexander
    Ocampo, Corinne
    Harder, Lena
    Gieseke, Friederike
    Pollmann, Annika
    Dierck, Kevin
    Prall, Sebastian
    Staege, Hannah
    Ma, Hui
    Horstmann, Martin A.
    Evans, Ronald M.
    Sternsdorf, Thomas
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (33) : 12133 - 12138
  • [6] Role of cytoplasmic forms of PML and PML-RARα in the response to therapy
    Bellodi, Cristian
    Kindle, Karin
    Bernassola, Francesca
    Dinsdale, David
    Cossarizza, Andrea
    Melino, Gerry
    Heery, David
    Salomoni, Paolo
    TOXICOLOGY, 2006, 226 (01) : 48 - 49
  • [7] Relationship between degradation of PML-RARα and differentiation
    Naoe, T
    Kitamura, K
    BLOOD, 1999, 94 (04) : 1478 - 1478
  • [8] Quantitation of PML-RARα transcripts in APL patients
    Tobal, K
    LEUKEMIA, 2000, 14 (08) : 1530 - 1531
  • [9] Quantitation of PML-RARα transcripts in APL patients
    K Tobal
    Leukemia, 2000, 14 : 1530 - 1531
  • [10] PML-RARα kills U937 cells:: A novel activity of PML-RARα that may contribute to APL pathogenesis.
    Lane, AA
    Westervelt, P
    Ley, TJ
    BLOOD, 2002, 100 (11) : 538A - 538A